Community-Acquired Urinary Tract Infections: Epidemiology, Etiology, and β-Lactam Resistance | ||||
| Sohag Journal of Sciences | ||||
| Volume 9, Issue 1, March 2024, Page 47-55 PDF (671.99 K) | ||||
| Document Type: Regular Articles | ||||
| DOI: 10.21608/sjsci.2023.226098.1103 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Magdy A. Abu-Gharbia; Gehad Al-Arabi ; Jehan M. Salem 
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| Botany and Microbiology Department, Faculty of Science, Sohag University, 82524 Sohag, Egypt. | ||||
| Abstract | ||||
| Urinary tract infection is considered a serious public health problem. One hundred and fifty patients were included in the present study and suspected to have community-acquired urinary tract infections depending on crucial indicators. Out of 150 urine cultures, 69.3% were confirmed as urinary tract infection with significant growth and 30.7% was sterile pyuria. Community-acquired urinary tract infections showed high incidence in females (44.1%), followed by kids (32.3%; 19.6% girls and 12.7% boys), and males (23.5%) with differences regarding age groups. Gram staining indicated that 63.2% of total isolated uropathogens were gram-negative isolates, and 36.7% were gram-positive isolates. The identification of 106 bacterial isolates led to the presence of 16 distinct species belonging to 12 genera including Escherichia coli (40.56%), Enterococcus spp. (18.86%), Streptococcus spp. (10.37%), Klebsiella spp. (8.49%), Citrobacter koseri (6.60%), Corynebacterium urealyticum (4.71%), Proteus mirabilis (2.83%), Enterobacter intermedius (1.88%), Pseudomonas aeruginosa (1.88%), Staphylococcus saprophyticus (1.88%), Serratia fonticola (0.94%) and Bacillus cereus (0.94%). Phenotypic detection of ESBL revealed that 35.8% of total isolated gram-negative uropathogens were ESBL-producers. Escherichia coli comprised a serious threat as the most dominant ESBL-producing organism representing 66.7% of total ESBL-producing bacteria detected followed by Klebsiella pneumonia (12.5%), Citrobacter koseri (8.3%), Serratia fonticola (4.1%), Proteus mirabilis (4.1%), and Pseudomonas aeruginosa (4.1%). | ||||
| Keywords | ||||
| Urinary Tract Infection; CA-UTIs; β-lactam; Enterobacteriaceae; ESBL | ||||
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