SQUALENE EXPLORING ITS VITAL ROLES IN VACCINE PRODUCTION, SKINCARE, CHOLESTEROL METABOLISM, ANTI-CANCER STRATEGIES, CARDIOVASCULAR HEALTH, AND ANTIOXIDANT POTENCY | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 30, Volume 47, Issue 1, June 2024, Page 437-448 PDF (648.81 K) | ||||
Document Type: Review Article | ||||
DOI: 10.21608/bfsa.2023.229536.1871 | ||||
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Authors | ||||
BASIM SALEEM AHMED ![]() ![]() | ||||
1zakho | ||||
2college of science dohuk university | ||||
Abstract | ||||
Abstract Squalene (SQ) is a naturally occurring hydrocarbon compound found abundantly in various sources, including shark liver, olive, and plant oils. SQ plays a pivotal role as a precursor molecule in humans and animals in synthesizing vitamins, cholesterol, and steroid hormones, maintaining healthy skin, and protecting against UV radiation-induced carcinogenesis. In the realm of medicine, SQ has emerged as a promising adjuvant in vaccines. Its role in enhancing immune responses has been studied extensively, contributing to the efficacy of influenza and COVID-19 vaccines. SQ has been confirmed to possess strong anti-tumor activity and inhibitory features against the development of cancer. Because of this, it is frequently used as a supplementary treatment for many forms of cancer. Intriguing and hopeful are the epidemiologic and laboratory studies looking into SQ's anti-cancer properties. Furthermore, SQ's stability during storage and technological processes adds to its appeal as a dietary supplement and functional ingredient in various food products. Additionally, as research progresses, the understanding of SQ's safety and efficacy continues to expand, providing a solid foundation for exploring its potential in various applications. This article study focuses on exploring the multifaceted uses of SQ in medicine, cosmetics, and nutrition. | ||||
Keywords | ||||
Antioxidant; Squalene; Vaccine; Skin disorder; Anti-cancer | ||||
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