Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative
Sultan, M., Kassem, A., Moharam, M., Taha, G. (2024). Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative. EKB Journal Management System, 67(4), 423-438. doi: 10.21608/ejchem.2023.227250.8374
Maha Sultan; Asmaa F. Kassem; Maysa E. Moharam; Ghada Taha. "Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative". EKB Journal Management System, 67, 4, 2024, 423-438. doi: 10.21608/ejchem.2023.227250.8374
Sultan, M., Kassem, A., Moharam, M., Taha, G. (2024). 'Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative', EKB Journal Management System, 67(4), pp. 423-438. doi: 10.21608/ejchem.2023.227250.8374
Sultan, M., Kassem, A., Moharam, M., Taha, G. Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative. EKB Journal Management System, 2024; 67(4): 423-438. doi: 10.21608/ejchem.2023.227250.8374

Investigation of A Novel Antimicrobial Chitosan Packaging Hydrogel Film Based On Azoloazine Derivative

Egyptian Journal of Chemistry
Volume 67, Issue 4, April 2024, Page 423-438  XML PDF (2.94 MB)
Document Type: Original Article
DOI: 10.21608/ejchem.2023.227250.8374
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Authors
Maha Sultan1; Asmaa F. Kassem2; Maysa E. Moharam3; Ghada Taha email orcid 4
1Packaging Materials Department, National Research Centre, 33 El Bohouth St. (former El Tahrirst.), Dokki, Giza, Egypt, P.O. 12622 Tel/ Fax, (202) 33322418 (202) 33370931
2Chemistry of Natural and Microbial Products Department, National Research Centre, 33 El Bohouth St. (former El Tahrirst.), Dokki, Giza, Egypt, P.O. 12622 Tel/ Fax, (202) 33322418 (202) 33370931
3Microbial Chemistry Department, National Research Centre, 33 El Bohouth St. (former El Tahrirst.), Dokki, Giza, Egypt, P.O. 12622 Tel/ Fax, (202) 33322418 (202) 33370931
4Pre-treatment and Finishing of Cellulose-based TextilesDepartment National Research Centre, 33 El Bohouth St. (former El Tahrirst.), Dokki, Giza, Egypt, P.O. 12622 Tel/ Fax, (202) 33322418 (202) 33370931
Abstract
The purpose of this work is to develop a novel active packaging chitosan hydrogel film (H17@CH) containing azoloazine derivatives as a novel antibacterial agent (11-(2-chlorobenzylidene)-6-(2-chlorophenyl)-6a, 7, 8, 9, 10, and 11-hexahydro-6H-benzo[b] (cyclohepta[e][1,4]thiazepine). The H17 revealed significant cell viability. H17 was added to chitosan in various quantities (100, 130, and 150µg). Significant cell viability was found in the H17. Chitosan was mixed with H17 in varying concentrations (100, 130, and 150 µg). Escherichia coli, Staphylococcus aureus, and Candida albicans are all susceptible to the antibacterial effects of the films. The films were evaluated using ATR-IR, XRD, XPS spectroscopy, and SEM-EDS. The maximum swelling ratio was 69.413.9 g/g for H17(100)@CH. The H17(150)@CH film had the lowest WVP at 15.601.52 g.mm. kPa-1.h-1.m-2. Guggenheim-Anderson-de Boer, Peleg, and Smith were utilized to model the water vapor adsorption isotherms. All of the models were perfectly fitted
Keywords
Chitosan; Azoloazine Derivative Packaging Hydrogel Film
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