COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study
Etman, M., Sofy, M., Abd El-Samie, A. (2023). COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study. EKB Journal Management System, 27(5), 23-31. doi: 10.21608/egyfs.2023.320843
Mohamed K. Etman; Marwa S. Sofy; Abd El-Samie A. Abd El-Samie. "COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study". EKB Journal Management System, 27, 5, 2023, 23-31. doi: 10.21608/egyfs.2023.320843
Etman, M., Sofy, M., Abd El-Samie, A. (2023). 'COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study', EKB Journal Management System, 27(5), pp. 23-31. doi: 10.21608/egyfs.2023.320843
Etman, M., Sofy, M., Abd El-Samie, A. COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study. EKB Journal Management System, 2023; 27(5): 23-31. doi: 10.21608/egyfs.2023.320843

COVID-19 disease effect on ovarian reserve in women of reproductive age: an analytical before-and-after COVID-19 study

The Egyptian Journal of Fertility of Sterility
Article 5, Volume 27, Issue 5 - Serial Number 11106352, September 2023, Page 23-31  XML PDF (1.47 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2023.320843
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Authors
Mohamed K. Etman email orcid 1; Marwa S. Sofy2; Abd El-Samie A. Abd El-Samie3
1Assistant professor of Obstetrics and gynecology department, Faculty of Medicine, Fayoum University.
2Resident of obstetrics and gynecology, Fayoum health insurance Hospital
3Professor of Obstetrics and Gynecology, Faculty of Medicine - Fayoum University
Abstract
Background: COVID-19 is a serious pandemic that affected multiple systems in the human body. Its effect on female fertility is not widely evaluated. 
Objective: to evaluate the effect of COVID-19 infection on the ovarian reserve and menstrual cycle in infertile women undergoing an assisted reproductive technology protocol.  
Study design: A cross-sectional analytical study was conducted on 120 infertile (primary or secondary infertility) women attending the Gynecology and Obstetrics Department at Fayoum University Hospital with confirmed previous COVID-19 disease. The ovarian reserve in this group was studied using AMH, AFC, and serum FSH, LH. The menstrual cycle length was evaluated before and after infection.  
Results: We studied 120 infertile women with confirmed COVID-19 infection. The average age was 26.96 ±5.68 years. Out of the 120 cases, 86 cases (71.7%) were diagnosed as mild COVID-19 infection, while severe cases were reported in 30 (25%), and only four women (3.3%) reported a moderate form of the infection. AMH, AFC, FSH and LH mean serum levels tested post-COVID-19 showed non-statistically significant difference in pre and post covid with infection (p-values > 0.05). A great proportion of the patients reported no change in the cycle length (63.3%) with insignificant difference reported between patients with mild, moderate, and severe infection (P value 0.874).
Conclusion: It was found that COVID-19 has no effect on ovarian reserve.
Keywords
Keywords: COVID-19; Ovarian Reserve; AMH; AFC; FSH; LH.   
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