Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness
Aboulnasr, T., Mohamed, A., Tabl, M., Abdel Hamid, N. (2023). Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness. EKB Journal Management System, 40(Special issue (ophthalmology)), 132-146. doi: 10.21608/bmfj.2023.238068.1908
Tarek Tawfik Aboulnasr; Ahmed Elhusseiny Mohamed; Marwa Abdelshafy Tabl; Nesma Zainhom Abdel Hamid. "Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness". EKB Journal Management System, 40, Special issue (ophthalmology), 2023, 132-146. doi: 10.21608/bmfj.2023.238068.1908
Aboulnasr, T., Mohamed, A., Tabl, M., Abdel Hamid, N. (2023). 'Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness', EKB Journal Management System, 40(Special issue (ophthalmology)), pp. 132-146. doi: 10.21608/bmfj.2023.238068.1908
Aboulnasr, T., Mohamed, A., Tabl, M., Abdel Hamid, N. Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness. EKB Journal Management System, 2023; 40(Special issue (ophthalmology)): 132-146. doi: 10.21608/bmfj.2023.238068.1908

Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness

Benha Medical Journal
Article 479, Volume 40, Special issue (ophthalmology), November and December 2023, Page 132-146  XML PDF (576.19 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2023.238068.1908
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Authors
Tarek Tawfik Aboulnasr1; Ahmed Elhusseiny Mohamed1; Marwa Abdelshafy Tabl2; Nesma Zainhom Abdel Hamid email 3
1Professor of Ophthalmology Faculty of medicine – Benha University
2Assistant Professor Ophthalmology Faculty of medicine – Benha University
3Department of Ophthalmology Faculty of medicine – Benha University
Abstract
Background: Age-related changes in ocular structures and function are of strong interest in knowing the impact of aging on visual health. Optical Coherence Tomography (OCT) has proven to be a valuable tool in assessing retinal nerve fiber layer (RNFL) thickness and macular ganglion cell complex (GCC), as indicators of retinal health. This study aimed to study age-associated change in peripapillary RNFL thickness and macular ganglion cell complex in healthy participants measured with the SD-OCT device. Methods: This prospective observational cross-sectional and analytical research- was performed on Eighty patients; divided into 4 groups (twenty eyes in each group) with age range 20-29, 30-39, 40-49 and 50-59 years old. All cases underwent to demographic and full ophthalmic investigation. Results: The results revealed considerable changes in and age terms, with females showing a significantly higher prevalence in the studied groups. Considerably higher ages were detected in Group IV than the other three groups, in Group III than in both Group II and I, and in Group II than Group I. Regarding retinal parameters, the study noticed significantly different in temporal RNFL thickness among Group I and IV (P-value < 0.05) also between Group II and IV (P-value < 0.05). Conclusions: RNFL thickness of healthy subjects was associated with age, particularly in the temporal areas. There was no considerable change between the groups investigated as regard (superior macular RNFL, inferior macular RNFL, and total macular RNFL). Age-associated RNFLT in healthy participants assessed using OCT does not detect the same slope in every sector/quadrant.
Keywords
Age-Related Changes; RNFL; Ganglion Cell Complex; OCT; Peripapillary RNFL Thickness
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