Endotype Conformity with Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) Score in Chronic Rhinosinusitis | ||||
Egyptian Journal of Ear, Nose, Throat and Allied Sciences | ||||
Article 48, Volume 24, Issue 24, January 2023, Page 1-7 PDF (376.03 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejentas.2023.185570.1600 | ||||
View on SCiNiTO | ||||
Authors | ||||
Iriana Maharani1; Finna Christianty 2; Edi Handoko3; Nanik Setijowati4 | ||||
1Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Brawijaya University/RSUD Dr. Saiful Anwar, Malang, Indonesia | ||||
2Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Brawijaya University /Dr. Saiful Anwar General Hospital, Malang, Indonesia | ||||
3Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Brawijaya University/Dr. Saiful Anwar General Hospital, Malang, Indonesia | ||||
4Department of Public Health, Faculty of Medicine, Brawijaya University | ||||
Abstract | ||||
Introduction: Chronic rhinosinusitis (CRS) is one of the most prevalent disease entities in ORL-HNS field. Management strategy of CRS remains challenging among otorhinolaryngologist. Currently, CRS was known as a heterogeneous disease with various endotypes and phenotypes. By identifying endotypes, comprehensive management strategy in CRS was expected. The Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) score was a categorical score developed from Japan to diagnose eosinophilic chronic rhinosinusitis (eCRS) and non-eosinophilic chronic rhinosinusitis (non-eCRS). The assessment of JESREC score was expected to have conformity with CRS endotypes so that it can be used as future efficient diagnostic modality. Objective: This study aims to determine conformity and accuracy of endotype with JESREC score. Patients and Methods: An analytic study with a cross-sectional design involving 33 samples of primary CRS. Biomarker for specific endotypes measured by ELISA. Results: Statistical analysis with Mc. Nemar showed no difference/ a conformity between JESREC score and CRS endotypes (p>0.05) with sensitivity 61,5% and specificity 90%. Conclusion: JESREC score is considered a screening modality for CRS endotype | ||||
Keywords | ||||
Chronic rhinosinusitis; endotype; JESREC; phenotype | ||||
Statistics Article View: 80 PDF Download: 156 |
||||