Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals
Abdelwahed, Z., Darwish, S., Elmashad, N., Tawfik, H. (2023). Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals. EKB Journal Management System, 7(3), 85-95. doi: 10.21608/jcbr.2023.220856.1307
Zeinab Mohamed Abdelwahed; Sara Abdelrahman Darwish; Nehal Mohamed Elmashad; Hesham Ahmed Tawfik. "Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals". EKB Journal Management System, 7, 3, 2023, 85-95. doi: 10.21608/jcbr.2023.220856.1307
Abdelwahed, Z., Darwish, S., Elmashad, N., Tawfik, H. (2023). 'Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals', EKB Journal Management System, 7(3), pp. 85-95. doi: 10.21608/jcbr.2023.220856.1307
Abdelwahed, Z., Darwish, S., Elmashad, N., Tawfik, H. Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals. EKB Journal Management System, 2023; 7(3): 85-95. doi: 10.21608/jcbr.2023.220856.1307

Clinico-Epidemiological Study of Pancreatic, Gall Bladder and Biliary Tract Cancers at Clinical Oncology Department Tanta University Hospitals

Egyptian Journal of Cancer and Biomedical Research
Volume 7, Issue 3, September 2023, Page 85-95  XML PDF (1.27 MB)
Document Type: Original Article
DOI: 10.21608/jcbr.2023.220856.1307
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Authors
Zeinab Mohamed Abdelwahed email 1; Sara Abdelrahman Darwish2; Nehal Mohamed Elmashad2; Hesham Ahmed Tawfik2
1Clinical Oncology & Nuclear Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
2Clinical Oncology & Nuclear Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Abstract
Background: In Egypt, pancreatic cancer (PC) is the 11th most prevalent malignancy and represents 2.2% of all cancers. PCs cause 3.2% of cancer deaths, ranking 8th. Gall bladder cancers account for 0.70% of malignancies in Egypt. Gall bladder cancer accounts for 0.77% of cancer deaths. Gallbladder cancers account for 0.8% of male malignancies in Gharbia and 0.7% in females. This retrospective study aimed to determine the incidence of pancreatic, gall bladder and biliary tract cancers (BTCs), describe the clinico-pathological pattern of pancreatic, gall bladder and BTCs, and detect progression free survival (PFS), disease free survival (DFS) and overall survival (OS) in correlation with prognostic factors.

Methods: This retrospective hospital based clinico-epidemiological study was carried out on 299 patients who were histo-pathological proved pancreatic or biliary tract malignancies through the period from Jan 2015 to Dec 2020 at Clinical Oncology Department Tanta university Hospital.

Results: The estimated median OS for PC patients was 8 months, while the estimated median PFS was 4 months and the estimated median DFS was 7 months. As regard BTC, the estimated median OS was 12 months, the estimated median PFS was 3 and the estimated median DFS was 5 months.

Conclusions: We advocate for the use of genetic counselling after testing to educate families about specific genetic disorders, the risks and advantages of testing, disease management, and potential treatment choices. It is important to promote community-specific cancer prevention initiatives, especially those aimed at reducing cigarette use and treating hepatitis C.
Keywords
Pancreatic cancer; biliary tract cancer, disease-free survival; gall bladder; progression free survival
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