Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism
Matar, H., Abdelazeim, E., Sheir, R., Nasser, M., Ahmed, M. (2023). Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism. EKB Journal Management System, 4(4), 94-104. doi: 10.21608/ejmr.2023.221674.1416
Hazem Samy Matar; Esraa Adel Abdelazeim; Rania El-Sayed Sheir; Mona Zaky sherif Nasser; Mahmoud Hassan Ahmed. "Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism". EKB Journal Management System, 4, 4, 2023, 94-104. doi: 10.21608/ejmr.2023.221674.1416
Matar, H., Abdelazeim, E., Sheir, R., Nasser, M., Ahmed, M. (2023). 'Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism', EKB Journal Management System, 4(4), pp. 94-104. doi: 10.21608/ejmr.2023.221674.1416
Matar, H., Abdelazeim, E., Sheir, R., Nasser, M., Ahmed, M. Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism. EKB Journal Management System, 2023; 4(4): 94-104. doi: 10.21608/ejmr.2023.221674.1416

Study the Correlation of Diabetic Complications and Macrophage Erythroblast Attacher (MAEA) rs6815464 Gene Polymorphism

Egyptian Journal of Medical Research
Volume 4, Issue 4, October 2023, Page 94-104  XML PDF (628.89 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2023.221674.1416
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Authors
Hazem Samy Matar1; Esraa Adel Abdelazeim email 1; Rania El-Sayed Sheir1; Mona Zaky sherif Nasser2; Mahmoud Hassan Ahmed1
1Internal Medicine department, Faculty of Medicine, Beni-Suef University, Egypt
2clinical pathology department, Faculty of Medicine, Beni-Suef University, Egypt
Abstract
This study was designed to evaluate MAEA gene rs6815464 polymorphism as a risk factor of type 2 diabetes mellitus (T2DM) associated  microangiopathic complications in the Egyptian population. Our patients were divided into two groups; diabetic patients with complications (30) recruited from Diabetes, endocrine and internal medicine clinic, Beni-Suef university hospital, compared with age and sex matched normal volunteers acting as a control group (61). Our study showed that diabetic retinopathy was the most common microangiopathic complication of T2DM (97%) followed by (90%) of the patients had diabetic nephropathy, while (70%) of the patients had diabetic neuropathy. Nonalcoholic fatty liver disease (NAFLD) was significantly higher in diabetic patients than in controls (p < 0.0001*). No significant correlation of MAEA rs6815464 polymorphism with the occurrence of diabetic microangiopathic complications was observed.
Keywords
Type 2 diabetes mellitus; Microangiopathy; MAEA gene rs6815464 polymorphism; NAFLD
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