Level of Basic Fibroblast Growth Factor in Breast Cancer Patients | ||||
| Journal of High Institute of Public Health | ||||
| Article 8, Volume 29, Issue 4, October 1999, Page 725-730 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jhiph.1999.325380 | ||||
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| Authors | ||||
| Ashraf El-Ghandour1; Manal El-Sorady2; Amr Abdelaziz2; Magdy El Bordini3 | ||||
| 1Internal Medicine department, Faculty of Medicine, Alexandria University, Egypt | ||||
| 2Clinical Oncology department, Faculty of Medicine, Alexandria University, Egypt | ||||
| 3Clinical Pathology Department, Faculty of Medicine, Alexandria University, Egypt | ||||
| Abstract | ||||
| Serum basic fibroblast growth factor (bFGF) was determined before and after surgery in 40 female patients with cancer breast, 20 with no metastasis (group 1) & 20 had metastasis. Sixty percent of group I had elevated bFGF and showed a significant difference before and after surgery, while 80% of group II had elevated bFGF with no significant difference before and after surgery. The mean value of serum bFGF before surgery in group I was 7.64+2.96 and it was 4.91±1.89 after surgery compared 8.56±2.8 & 8.02±2.8 for group II. This indicate that bFGF has a direct relation to the tumor and its metastasis and surgery in non-metastatic tumor may normalized the level of bFGF and its increase may indicate metastasis. | ||||
| Keywords | ||||
| Basic Fibroblast; Growth Factor; Breast Cancer; Patients | ||||
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