The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial
Mohammed, M., Azab, N., Shaker, O., Hussine, A. (2023). The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial. EKB Journal Management System, 5(4), 901-915. doi: 10.21608/adjc.2023.216208.1336
Mona Taha Mohammed; Noha Adel Azab; Olfat Gamil Shaker; Amal Ali Hussine. "The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial". EKB Journal Management System, 5, 4, 2023, 901-915. doi: 10.21608/adjc.2023.216208.1336
Mohammed, M., Azab, N., Shaker, O., Hussine, A. (2023). 'The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial', EKB Journal Management System, 5(4), pp. 901-915. doi: 10.21608/adjc.2023.216208.1336
Mohammed, M., Azab, N., Shaker, O., Hussine, A. The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial. EKB Journal Management System, 2023; 5(4): 901-915. doi: 10.21608/adjc.2023.216208.1336

The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level Of Oxidative Stress Biomarker (MDA): Randomized Clinical Trial

Advanced Dental Journal
Volume 5, Issue 4, October 2023, Page 901-915  XML PDF (558.15 K)
Document Type: Original Article
DOI: 10.21608/adjc.2023.216208.1336
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Authors
Mona Taha Mohammed email 1; Noha Adel Azab1; Olfat Gamil Shaker2; Amal Ali Hussine1
1Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Egypt.
2Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Egypt.
Abstract
Objectives: To compare the effectiveness of topical sesame oil in the formulation of a gel and topical triamcinolone acetonide 0.1% in dealing with the signs and symptoms of OLP. Patients and Methods: This randomized, controlled trial had thirty four patients who were randomly allocated to receive either sesame oil gel or triamcinolone acetonide 0.1% gel thrice daily for 4 weeks.  We assessed pain using the visual analogue scale and erythema and ulceration using the Thongprasom score and salivary MDA by ELISA.  Results: Patients improved significantly in both groups, however change in the triamcinolone group occurred significantly faster than the sesame oil group. The Thongprasom score differed significantly between both groups (p< 0.001) favoring the triamcinolone group. The MDA level was statistically insignificant between both groups. Conclusion:  Sesame oil can relieve pain but not as quickly as triamcinolone acetonide, additionally, it has no detectable effect on improving the clinical picture of OLP.
Keywords
Triamcinolone acetonide; sesame oil; Thongprasome; VAS
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