Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19
Ahmed, H., Essa, E., Diaa Eldin, D., Moustafa Moussa, S., Mounir Ali, S. (2023). Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19. EKB Journal Management System, 10(2), 19-28. doi: 10.21608/ejgg.2023.325911
Heba Ahmed; Ekramy Essa; Dalia Diaa Eldin; Shereen Moustafa Moussa; Suzane Mounir Ali. "Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19". EKB Journal Management System, 10, 2, 2023, 19-28. doi: 10.21608/ejgg.2023.325911
Ahmed, H., Essa, E., Diaa Eldin, D., Moustafa Moussa, S., Mounir Ali, S. (2023). 'Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19', EKB Journal Management System, 10(2), pp. 19-28. doi: 10.21608/ejgg.2023.325911
Ahmed, H., Essa, E., Diaa Eldin, D., Moustafa Moussa, S., Mounir Ali, S. Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19. EKB Journal Management System, 2023; 10(2): 19-28. doi: 10.21608/ejgg.2023.325911

Prognostic Significance of Hematological Parameters in Hospitalized Elderly with COVID-19

The Egyptian Journal of Geriatrics and Gerontology
Article 2, Volume 10, Issue 2, October 2023, Page 19-28  XML PDF (424.3 K)
Document Type: Original Article
DOI: 10.21608/ejgg.2023.325911
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Authors
Heba Ahmed* 1; Ekramy Essa1; Dalia Diaa Eldin2; Shereen Moustafa Moussa1; Suzane Mounir Ali1
1Geriatrics and Gerontology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
2Clinical Pathology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Abstract
Aim: COVID-19 is a global pandemic; it caused more than 256 million cases, and early detection of patients at high risk of mortality is of great importance in saving the lives of COVID-19 patients. “In our study” we aimed to utilize the haematological parameters in predicting prognosis and mortality among elderly patients diagnosed with COVID-19 infection admitted at Geriatric isolation hospital, Ain Shams University during the period from 26/12/2020 to 20/6/2021.
Methods: This is a retrospective cohort study involving elderly patients admitted at the Geriatric isolation hospital, Ain Shams University during the period from 26/12/2020 to 20/6/2021.Retrospective evaluation of medical records was used to collect data. The study included patients older than 60 years with proof of SAR-CoV2 by nasopharyngeal swab. Serial complete blood count parameters were reported during admission: haemoglobin (Hb), Total leukocytic count (TLC), Neutrophils (N), lymphocytes (L), platelets (PLT), Red Cell Distribution Width (RDW), Neutrophil/lymphocyte(NLR), platelet/lymphocyte(PLR) ratios were calculated, other haematological parameters as C-reactive protein (CRP) and ferritin were reported.
Results: Among 50 hospitalized COVID-19 patients with a mean age of 68.5 years, 54% were males. Mortality of those patients has a statistically significant association with the presence of high NLR, CRP, Ferritin and lymphopenia on admission and the likelihood of patients’ mortality will rise with the presence of NLR>12.4, CRP>120mg/L, FERRITIN>493.6mcg/L and Lymphocytes≤0.88 *109/ L on admission, however, presence of CRP>120mg/L is an independent factor for mortality in hospitalized elderly with COVID 19.
Conclusion: Hematological parameters such as (NLR, CRP, Ferritin and lymphopenia) are predictor markers for mortality in hospitalized elderly with COVID-19.

Keywords
COVID-19; mortality; neutrophil/lymphocyte ratio (NLR); C-reactive protein (CRP); Ferritin
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