Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022
Flifel, A., Elshaer, N., Abdelhai, R., Nada, Y. (2023). Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022. EKB Journal Management System, 1(1), 39-49. doi: 10.21608/arcmed.2023.189614.1017
Amr Flifel; Noha Elshaer; Rehab Abdelhai; Yousery Nada. "Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022". EKB Journal Management System, 1, 1, 2023, 39-49. doi: 10.21608/arcmed.2023.189614.1017
Flifel, A., Elshaer, N., Abdelhai, R., Nada, Y. (2023). 'Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022', EKB Journal Management System, 1(1), pp. 39-49. doi: 10.21608/arcmed.2023.189614.1017
Flifel, A., Elshaer, N., Abdelhai, R., Nada, Y. Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022. EKB Journal Management System, 2023; 1(1): 39-49. doi: 10.21608/arcmed.2023.189614.1017

Risk Factors for Colorectal Cancer: A Case-control Study in Egypt, 2022

ARCADEs of MEDICINE
Volume 1, Issue 1, December 2023, Page 39-49  XML PDF (392.79 K)
Document Type: Original Research
DOI: 10.21608/arcmed.2023.189614.1017
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Authors
Amr Flifel email orcid 1; Noha Elshaerorcid 2; Rehab Abdelhaiorcid 3; Yousery Nadaorcid 4
1Public Health and Community Medicine, Armed Forces College of Medicine, Cairo Egypt
2Department of Community Medicine, Faculty of Medicine, Alexandria University, Alexandria; and Department of Public Health and Community Medicine, Armed Forces College of Medicine, Cairo
3Public Health and Community Medicine Faculty of Medicine, Cairo University
4Medical Oncology Department , Maadi Armed Forces Medical Compound, Cairo, Egypt.
Abstract
Background:

Colorectal cancer (CRC) is regarded as a genetic and lifestyle disease, where lifestyle and environmental factors might contribute substantially to its etiology. Identifying modifiable risk factors would be crucial for prevention. This study was conducted to determine the risk factors for CRC.

Methods:

A case-control study was conducted at the Maadi Armed Forces Medical Complex (MAFMC) in Egypt in 2022, including 101 cases and 101 controls. All participants underwent a face-to-face interview with a structured questionnaire to gather information about their sociodemographic characteristics, lifestyle, dietary and gastrointestinal habits, family, medical, and reproductive history, and occupational data. Regression analysis was done to model CRC as a function of the potential risk factors.

Results:

CRC was significantly associated with positive family history for CRC, not attaining higher education, not having a spouse, infrequent fruit and vegetable consumption, frequent consumption of processed meat, sedentary behavior and more than once per day bowel movement. The regression model correctly classified 72.3% of CRC cases and controls. Accordingly, four predictors of CRC were identified: a positive family history of CRC [OR = 8.70, 95% CI = 1.60, 48.8], sedentary behavior more than 6 hours per day [OR = 3.54, 95% CI = 1.60, 8.1], bowel movement more than once per day [OR = 2.07, 95% CI = 1.1, 4.1], and not attaining higher education [OR = 2.47, 95% CI = 1.3, 4.8].

Conclusion:

The study highlighted predictors of CRC to be considered in screening. Moreover, longitudinal multicentric studies with objective evaluations of exposures are required.
Keywords
Colorectal cancer; Egypt, Risk factors; Predictors
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