Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study)
Ibrahim, I., Mohamed, M., Edrees, M. (2023). Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study). EKB Journal Management System, 6(2), 179-185. doi: 10.21608/aadj.2023.326282
Ibrahim Hammad Ibrahim; Mostafa Mohamed Sameeh Mohamed; Mohamed Fouad Edrees. "Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study)". EKB Journal Management System, 6, 2, 2023, 179-185. doi: 10.21608/aadj.2023.326282
Ibrahim, I., Mohamed, M., Edrees, M. (2023). 'Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study)', EKB Journal Management System, 6(2), pp. 179-185. doi: 10.21608/aadj.2023.326282
Ibrahim, I., Mohamed, M., Edrees, M. Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study). EKB Journal Management System, 2023; 6(2): 179-185. doi: 10.21608/aadj.2023.326282

Evaluation of the Efficacy of Ciprofloxacin as Topical Adjunctive Therapy in Non-Surgical Treatment of Stage I and II Grade A Periodontitis (Clinical and Biochemical Study)

Al-Azhar Assiut Dental Journal
Volume 6, Issue 2, October 2023, Page 179-185  XML PDF (1 MB)
Document Type: Original Article
DOI: 10.21608/aadj.2023.326282
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Authors
Ibrahim Hammad Ibrahim email 1; Mostafa Mohamed Sameeh Mohamed2; Mohamed Fouad Edrees3
1Department of Oral medicine, Periodontology, Diagnosis and Oral radiology, Faculty of Dental Medicine, (Assiut, boys), Al-Azhar University, Egypt.
2Department of Oral medicine, Periodontology, Diagnosis and Oral radiology, Faculty of Dental Medicine, (Assiut, boys), Al-Azhar University, Egyp.
3Department of Oral medicine, Periodontology, Diagnosis and Oral radiology, Faculty of Dental Medicine, (Assiut, boys), Al-Azhar University, Egyp
Abstract
Aims: This study was performed to evaluate clinically and biochemically the 
efficacy of ciprofloxacin as adjunctive in non-surgical treatment of stage I and II Grade 
A periodontitis, through evaluation of the clinical parameters as well as IL-6 level 
in GCF.. Subjects and Methods: 20 patients of both sex divided into two groups. 
Group 1 included 10 patients were treated by only conventional periodontal therapy 
(scaling and root planing). Group 2 included 10 patients were treated by scaling and 
root planing followed by topical intra pocket application of Ciprofloxacin gel 1%. 
Evaluated clinically at baseline, 1 month and 3 months. The biochemical evaluation 
of interleukin 6 was done at baseline, 1 month and 3 months. Results: Clinical 
parameter showed a statistically significant differences in both groups at the different 
intervals when compared to the baseline. All parameter showed in group 2 statistically 
significant difference between 1 month and 3 month. When groups 2 was compared 
to group 1 all parameter showed statistically reduction at 1 month and 3 months in 
relation to baseline. Biochemical marker showed a statistically significant differences 
were showed in both groups at the different intervals when compared to the baseline 
with statistically significant difference between 1 month and 3 month. Conclusion: The 
topically applied ciprofloxacin seamed to exhibit a synergistic action in treatment of 
stage I and II grade A periodontitis
Keywords
Ciprofloxacin; periodontitis; synergistic action; root scaling; root planning
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