COVID-19 Vaccination Adverse Reactions among Vaccinated Persons in Mansoura University: A Prospective Study | ||||
| Egyptian Journal of Medical Microbiology | ||||
| Volume 33, Issue 1, January 2024, Page 37-48 PDF (616.48 K) | ||||
| Document Type: New and original researches in the field of Microbiology. | ||||
| DOI: 10.21608/ejmm.2024.326771 | ||||
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| Authors | ||||
Noha M. Mahmoud   1; Heba E. Eldegla2; Ragy N. Shenouda2; Amr S. Elsaeed3; Mohamed M. Mahmoud3; Doaa Alemam4; Nermin Y. Abo El Kheir5; Amira H. El-Ashry2
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| 1Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Medical Microbiology & Immunology Department, Faculty of Medicine, Horus University, New Damietta, Egypt | ||||
| 2Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt | ||||
| 3General Surgery Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt | ||||
| 4Public Health and Community Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Public Health and Community Medicine Department, Faculty of Medicine, Horus University, New Damietta, Egypt | ||||
| 5Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt | ||||
| Abstract | ||||
| Background: Health-care workers are at highest risk for COVID-19 and its complications. Vaccine development might be the best choice for ending this pandemic. Hence, studies are essential to follow the vaccination adverse reactions. Objectives: To determine the prevalence of adverse effects among COVID-19 vaccinated persons after getting the first and/or the second dosage of the vaccines. Methodology: This research was conducted on 509 vaccinated participants to investigate the adverse symptoms of the available COVID vaccines through an online survey. The questionnaire comprised 3 compartments; background, vaccination adverse symptoms and the comorbidities data. It was delivered to participants via social media. Results: Adverse symptoms were reported by more significant participants following the 1st dosage (n = 208, 80.0%) than following the 2nd dosage (n = 169, 67.9%) (P=0.002). The most prevalent adverse effects included fatigue, injection site pain, headache, fever, bone, and muscular pain. AstraZeneca and Sputnik led to more common adverse symptoms following 1st and 2nd doses. Females were more likely to experience post 1st dose (p=0.005) and 2nd dose (p=0.022) side effects. Resident doctors had higher odds (OR = 6.0 95% confidence interval [CI]:1.03 -35.1, p=0.029) than the other jobs to develop 1st dose post-vaccination effects. Participants with autoimmune and chronic diseases had a higher risk to develop post 1st dose adverse effects. Conclusion: About 80% of participants who obtained the COVID-19 vaccination experienced adverse effects. The most prevalent side effect following the 1st dosage was fatigue while pain at the injection site was the most prevalent symptom following the 2nd dosage. | ||||
| Keywords | ||||
| COVID-19 vaccine; Adverse reactions; Healthcare workers; injection site pain; online survey | ||||
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