Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. (2015). Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines. EKB Journal Management System, 28(1), 235-240. doi: 10.21608/bvmj.2015.32752
Gabr F. El-Bagoury; Saad S.A Sharawi; Ehab M. El-Nahas; Darwish M. Darwish; Mohammed A. Saad. "Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines". EKB Journal Management System, 28, 1, 2015, 235-240. doi: 10.21608/bvmj.2015.32752
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. (2015). 'Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines', EKB Journal Management System, 28(1), pp. 235-240. doi: 10.21608/bvmj.2015.32752
El-Bagoury, G., Sharawi, S., El-Nahas, E., Darwish, D., Saad, M. Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines. EKB Journal Management System, 2015; 28(1): 235-240. doi: 10.21608/bvmj.2015.32752

Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines

Benha Veterinary Medical Journal
Article 27, Volume 28, Issue 1, March 2015, Page 235-240  XML PDF (226.23 K)
Document Type: Original Article
DOI: 10.21608/bvmj.2015.32752
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Authors
Gabr F. El-Bagoury1; Saad S.A Sharawi1; Ehab M. El-Nahas1; Darwish M. Darwish2; Mohammed A. Saad2
1Department of virology, Faculty of Veterinary Medicine, Benha University
2Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo
Abstract
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of clovenhoofed
animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGY-A-2012) and
imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid
control of the disease. Our study aimed to determine the antigenic relatedness (R-value) of FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines
using serum neutralization test (SNT). At 28th day post vaccination with either local commercial or imported
vaccines, the calculated R-values for O/EGY-4-2012 were 0.84 with O Panasia-2 in local commercial
vaccine and 0.65 with O Manisa in imported vaccine. A/EGY/1/2012 showed R-value 0.78 and 0.72 with
A Iran-05 in local commercial and imported vaccines respectively. In conclusion, FMD virus Egyptian
isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported
vaccines, which provide good protection.
Keywords
Foot-and-mouth disease; R-value; serotypes O and A; vaccinal strains
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