Value of Platelet Indices in Evaluation of Varicocele Patients and Its Associated Abnormal Semen Parameters: A Cross Sectional Study | ||||
| International Journal of Medical Arts | ||||
| Article 1, Volume 5, Issue 10, October 2023, Page 3682-3686 PDF (883.51 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2023.238566.1821 | ||||
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| Authors | ||||
Mohamed Ibrahim Hossam Ahmed  1; Mohamed Ismail Kamel2; AbdElaleem AbdElaleem Elgendy3
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| 1Department of Dermatology, Venereology and Andrology, The Egyptian Ministry of Health, Cairo, Egypt | ||||
| 2Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||||
| 3Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Varicocele is present in up to 19–41% of men with primary infertility and 80% of men with secondary infertility. Varicocele is associated with abnormal semen parameters. The role of platelet indices [PIs] in many vascular diseases, including varicocele, has been widely studied. Aim of the Study: The aim of this study was to evaluate the platelet indices in varicocele patients and its value in association with abnormal semen parameters. Patients and Methods: A cross sectional study was conducted on 122 male patients with varicocele, recruited from Dermatology, Venereology & Andrology Outpatient Clinics in Al-Azhar University Hospitals, Cairo, Egypt. The patients were classified into two groups [61 patients with varicocele associated with normal semen parameters and 61 patients with varicocele associated with abnormal semen parameters]. All patients were subjected to history taking, general and genital examination, complete blood count [CBC] and Scrotal Doppler Ultrasound. PIs were then compared between the two groups by their characteristics and grade of varicocele using appropriate statistical tests. Results: Of the studied platelet indices, the mean platelet volume [MPV] and plateletcrit [PCT] were significantly higher in varicocele group associated with abnormal semen parameters compared to varicocele group associated with normal semen parameters [9.5 ± 1.4 vs. to 7.9 ± 0.98; and 0.22 ± 0.05 vs. 0.18 ± 0.04]. In the varicocele group associated with abnormal semen parameters, the mean PCT and platelet distribution width [PDW] were significantly higher in the studied varicocele grades II and III compared to grade I. A significant moderate positive correlation was found between MPV and PCT and the number of sperms in the varicocele group associated with abnormal semen parameters. Conclusion: The study findings indicating that MPV and PCT were significantly higher in Varicocele patients with abnormal semen parameters than in normospermic varicocele patients. | ||||
| Keywords | ||||
| Platelets; Platelet indices; Mean platelet volume; Varicocele; Semen | ||||
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