Correlation of Epicardial Fat Thickness and Severity of Coronary Plaque Lesion Using Echocardiography and Cardiac Multidetector Computed Tomography | ||||
| Zagazig University Medical Journal | ||||
| Articles in Press, Accepted Manuscript, Available Online from 03 December 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2023.250813.3013 | ||||
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| Authors | ||||
Radwa Mohammad Abdalla1; Magdy Mohamed AbdSamee2; Mohammad Gouda3; Mohammad Mahmoud  4; Shaimaa Wageeh 5
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| 1department of Cardiology and Vascular Diseases, Faulty of Medicine, Zagazig University | ||||
| 2cardiology department,zagazig Zagazig University | ||||
| 3Cardiology Department, Faculty of Medicine , Zagazig University, Egypt | ||||
| 4Cardiology Department, Faculty of Medicine, Zagazig University | ||||
| 5Cardiology Department, Faculty of Medicine, Zagazig University, Egypt. | ||||
| Abstract | ||||
| Background: Epicardial fat considered a part of visceral fat depot; it surrounds the myocardium just underneath the visceral pericardium where it has close proximity to the coronaries. Researches proof that epicardial adipose tissue is biologically active and so may had a significant role in the occurrence and severity of atherosclerotic CAD. Advances in cardiovascular imaging techniques make echocardiography and MDCT accurate enough to assess both EFT and EFV respectively. Patients and Methods: One hundred participants were recruited in this cross sectional study from January to December 2022. Patients were referred to Kobri El Kobba Military Hospital with suspected CAD for multi-slice CT angiography. Results: Patients were classified into two groups according to the results of the CT coronary angiography; group (I) with significant CAD, 82 cases and group (II) without significant CAD, 18 cases. There was a statistically significant difference between group I and group II regarding BMI, HTN, DM, total cholesterol, LDL, HDL, triglycerides, LDL/HDL ratio, EF (%), RSWMA, Epicardial Fat volume (EFV) measured by MDCT and EFT measured by Echocardiography. There was no statistically significant difference between the subgroups Ia, Ib and Ic regarding EFT measured by Echocardiography. EFV measured by MDCT is the most statistically significant predictor for severe CAD or multi-vessel disease. Conclusion: Epicardial fat depot was significantly associated with plaque development and vulnerability where EFT and EFV showed high values and were closely related to CAD presence and severity. | ||||
| Keywords | ||||
| Epicardial Fat Thickness; Epicardial fat volume, Coronary Plaque; Echocardiography; Cardiac ‎ Multidetector Computed Tomography. &lrm | ||||
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