Green Analytical Chemistry to Eco-Friendly HPLC Techniques in Pharmaceutical Analysis: A Review | ||||
| Egyptian Journal of Veterinary Sciences | ||||
| Volume 55, Issue 3, May and June 2024, Page 795-801 PDF (694.9 K) | ||||
| Document Type: Review Artical | ||||
| DOI: 10.21608/ejvs.2023.234808.1667 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Maha, S. Abd-Elhafeez 1; Mahmoud M. Arafa2; Fatma H. Amro 3; Fady Sayed Youssef  4
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| 1Chemistry, Toxicology and Feed Deficiency Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Giza 12619, Egypt. | ||||
| 2Feed deficiency unit, Chemistry, toxicology, and feed deficiency department, Animal Health Research Institute, Agriculture Research Center, Giza | ||||
| 3Reference laboratory of veterinary Quality Control on Poultry Production (RLQP), Animal Health Research Institute ( AHRI), Agriculture Research Center (ARC), Giza 12619, Egypt. | ||||
| 4Department of Pharmacology, faculty of veterinary Medicine, Cairo university | ||||
| Abstract | ||||
| Green Chemistry (GC) is designing chemical processes and products to decrease the use of harmful materials, based on 12 theories established in 1998. The pharmaceutical industry faces a significant problem due to the worldwide requirement to comply with Green Analytical Chemistry (GAC) requirements. High-pressure liquid chromatography (HPLC) is a widely used process in the medicine industry, but it produces massive quantities of organic hazardous waste. Analytical techniques must be optimized for precision, sensitivity, repeatability, effortlessness, cost effectiveness, versatility, and speed. Though, other factors such as analysts’ security and ecological effects are rarely considered. Although there are more publications about green chromatography techniques, there has not been much adoption of eco-friendly HPLC techniques in the pharmaceutical business. The major causes of this are the need for adapting the standard HPLC apparatus, a lack of time, knowledge, or analysts' confusion over the fulfilment of the method requirements. An overview of green approaches for liquid chromatography (LC) that may be quickly applied to traditional instruments was provided to create eco-friendly HPLC procedures for pharmaceutical analysis. | ||||
| Keywords | ||||
| Green Analytical Chemistry; HPLC; Pharmaceutical analysis | ||||
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