Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic
bdreldien, Y., Abou-Dobara, M., El-Sayed, A., Zaghloul, M. (2023). Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic. EKB Journal Management System, 13(3), 71-78. doi: 10.21608/sjdfs.2023.230321.1127
yahya anwar bdreldien; Mohamed I. Abou-Dobara; Ahmed K.A. El-Sayed; Mohamed Hossam Zaghloul. "Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic". EKB Journal Management System, 13, 3, 2023, 71-78. doi: 10.21608/sjdfs.2023.230321.1127
bdreldien, Y., Abou-Dobara, M., El-Sayed, A., Zaghloul, M. (2023). 'Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic', EKB Journal Management System, 13(3), pp. 71-78. doi: 10.21608/sjdfs.2023.230321.1127
bdreldien, Y., Abou-Dobara, M., El-Sayed, A., Zaghloul, M. Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic. EKB Journal Management System, 2023; 13(3): 71-78. doi: 10.21608/sjdfs.2023.230321.1127

Morphological and Ultrastructural Changes of Escherichia coli and Klebsiella pneumoniae carriers of β-lactamase when subject to β-lactam Antibiotic

Scientific Journal for Damietta Faculty of Science
Volume 13, Issue 3, December 2023, Page 71-78  XML PDF (751.29 K)
Document Type: Original articles
DOI: 10.21608/sjdfs.2023.230321.1127
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Authors
yahya anwar bdreldien email 1; Mohamed I. Abou-Dobara2; Ahmed K.A. El-Sayed3; Mohamed Hossam Zaghloul4
1Botany and Microbiology Department, Faculty of Science, Damietta
2Botany Dept., Faculty of Sci., Damietta Univ., New Damietta, P.O. 34517, Egypt
3Botany
4clinical pathology faculty of medicine mansoura university
Abstract
In our manuscript, we examine the structure and morphology, we take an imperative look at this pathway. We collected clinical isolates from patients at the Oncology Center of Mansoura University, from urine samples. The isolates were then screened for antibiotic resistance and beta-lactamase enzyme production, with a focus on the most prevalent bacterial isolates. To further investigate the impact of one particular beta-lactam antibiotic on Escherichia coli and Klebsiella pneumoniae, both known producers of the beta-lactamase enzyme, we utilized Transmission Electron and Scanning Electron Microscopes. Our study aims to discuss the various changes induced by cefoxitin, including its effects on the characteristics of clinical isolates such as the cell wall structure of E. coli and K. pneumoniae.

The aim of this manuscript is to discuss the occurrence of alterations caused by beta-lactam antibiotics. Photomicrographs will be used to describe these alterations and provide information about the agents responsible for the changes. We will focus on the structural and morphological changes that are consistently observed.
Keywords
Beta-lactam antibiotic; Mechanism of action; Scanning Electron Microscopy; Transmission Electron Microscopy; Bacterial morphological changes
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