Protective effect of remifentanil on blood loss in endoscopic subcutaneous mastectomy: a retrospective study | ||||
| Ain-Shams Journal of Anesthesiology | ||||
| Volume 10, Issue 1, October 2018 PDF (976.54 K) | ||||
| DOI: 10.1186/s42077-018-0008-4 | ||||
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| Authors | ||||
Satoshi Yamaguchi   ; Kyoichi Nakamura; Osamu Kobayashi; Yukio Takahashi; Kenji Sato; Michio Shimabukuro
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| Abstract | ||||
| Background Remifentanil decreases blood loss during spinal surgery, rhinoplasty, and endoscopic sinus surgery. However, there are no reports regarding its effect on intraoperative blood loss during endoscopic body surface surgery. The present study aimed to investigate the effect of intraoperative remifentanil on blood loss during endoscopic subcutaneous mastectomy. Methods In this single-center, retrospective observational study conducted from August 2005 to June 2010, 443 patients who underwent either endoscopic subcutaneous partial mastectomy or quadrantectomy were included ( = 231 and 212, respectively). Patients were categorized into the remifentanil and non-remifentanil groups ( = 154 and 289, respectively) based on intraoperative use of remifentanil. We compared the amount of blood loss between the remifentanil and non-remifentanil groups. Results Blood loss was significantly smaller in the remifentanil group than in the non-remifentanil group in patients undergoing partial mastectomy (median [25%, 75%], 60 [30, 94] vs. 90 [50, 165] ml, < 0.001) and quadrantectomy (90 [30, 163] vs. 140 [74, 220] ml, = 0.001). Conclusions Intraoperative bleeding was significantly smaller in patients receiving remifentanil than that in those not receiving remifentanil during endoscopic subcutaneous mastectomies. | ||||
| Keywords | ||||
| Anesthesiology; blood pressure; Remifentanil; mastectomy; blood loss; Endoscopy | ||||
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