Curcumin Mimics: An Overview

Elrayess, Ranza Ahmed; Abdel-Wahab, Sherief M.; Yassen, Asmaa SA; Attia, Khadiga M; Elshihawy, Hosam A.

doi:10.21608/rpbs.2023.246345.1251

	Curcumin Mimics: An Overview
Records of Pharmaceutical and Biomedical Sciences
Volume 7, Issue 1, January 2023, Page 189-196 PDF (539.28 K)
Document Type: Mini-reviews
DOI: 10.21608/rpbs.2023.246345.1251
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Authors
Ranza Ahmed Elrayess ¹; Sherief M. Abdel-Wahab²; Asmaa SA Yassen ³; Khadiga M Attia²; Hosam A. Elshihawy³
¹Department of Pharmaceutical organic chemistry, faculty of pharmacy, Suez canal University, Ismailia, Egypt
²Pharmaceutical Organic Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt
³Pharmaceutical Organic Chemistry, School of Pharmacy, Suez Canal University
Abstract
Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics. Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics.
Keywords
Curcumin; Anti-cancer; Anti-inflammatory; Curcumin mimetics


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