Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital
M. Eltabey, S., H. Ibrahim, A., M. Zaky, M., M. Saleh, M. (2024). Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital. EKB Journal Management System, 5(1), 63-75. doi: 10.21608/ajbas.2023.246493.1195
Sara M. Eltabey; Ali H. Ibrahim; Mahmoud M. Zaky; Moustafa M. Saleh. "Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital". EKB Journal Management System, 5, 1, 2024, 63-75. doi: 10.21608/ajbas.2023.246493.1195
M. Eltabey, S., H. Ibrahim, A., M. Zaky, M., M. Saleh, M. (2024). 'Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital', EKB Journal Management System, 5(1), pp. 63-75. doi: 10.21608/ajbas.2023.246493.1195
M. Eltabey, S., H. Ibrahim, A., M. Zaky, M., M. Saleh, M. Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital. EKB Journal Management System, 2024; 5(1): 63-75. doi: 10.21608/ajbas.2023.246493.1195

Antimicrobial Susceptibility and Resistance Profile of Escherichia coli Isolates from Patients at Suez Canal University Specialized Hospital

Alfarama Journal of Basic & Applied Sciences
Volume 5, Issue 1, January 2024, Page 63-75  XML PDF (1.04 MB)
Document Type: Original Article
DOI: 10.21608/ajbas.2023.246493.1195
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Authors
Sara M. Eltabey email 1; Ali H. Ibrahim2; Mahmoud M. Zaky2; Moustafa M. Saleh3
1Microbiology program, Botany Department, Faculty of Science, Port Said University, Egypt
2Botany Department, Faculty of Science, Port Said University, Port Said, Egypt.
3Microbiology and Immunology Department, Faculty of Pharmacy, Port Said University, Port Said, Egypt. .
Abstract
Antibiotics have increased our lifespan by more than 20 years and shielded us from dangerous microbes. However, their power is dwindling. Therefore, antibiotic resistance is a current worldwide health emergency, and it could be the following pandemic. Thus, the present study assesses the susceptibility and resistance pattern of various E. coli isolates collected from patients at Suez Canal University Specialized Hospital. Collectively, 50 isolates of E. coli out of 150 specimens were isolated from different specimens’ types (urine, stool, and blood) and were identified using traditional standard protocols. After performing antibiotic susceptibility testing, the overall tested isolates showed the highest susceptibility against MRP (92%) followed by AK (90%), while the highest resistance was obtained against AMC (100%) followed by CTX (44%). On the other hand, E. coli isolates from urine showed the highest susceptibility against MRP and AK (91.43%) each, while the highest resistance was against AMC (100%) followed by CTX (51.43%). Moreover, the maximum susceptibility of stool isolates was against AK and MRP (83.33 %) each, whereas the isolates obtained from stool showed the highest resistance against AMC (100%) followed by CTX (50%) each. Finally, the E. coli isolates from blood revealed the superior susceptibility to MRP (88.89%) followed by LEV, AK, and DO (77.78%), while the highest resistance of blood specimens was found against AMC (100%) followed by CTX (33.33%). Furthermore, the resistance patterns revealed that 66% of the isolates were MDR. Finally, it is crucial to evaluate the antimicrobial sensitivity test for effective therapy.
Keywords
Escherichia coli; Antimicrobial Susceptibility; Antibiotic Resistance; E. coli Infections; Multi-Drug Resistant
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