Complications of Growth Hormone administration in Poor Ovarian Reserve undergoing ICSI. A Randomized Control study | ||||
Medicine Updates | ||||
Volume 16, Issue 16, January 2024, Page 23-28 PDF (1.12 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/muj.2023.258185.1159 | ||||
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Authors | ||||
Ola Mohamed Metawie 1; Mohamed Hafez Younis2; Waleed Elsayed Elrefaie3; Hesham Anany4 | ||||
1Department of Obstetrics and Gynecology, | ||||
2Department Of Obstetrics and Gynecology, Portsaid University | ||||
3Department of Obstetrics and Gynecology, Port Said University | ||||
4Department of Obstetrics and Gynecology, Cairo University | ||||
Abstract | ||||
Introduction Poor ovarian reserve (POR) is considered a serious condition that affects couples. There are different medical modalities and intervention trying to overcome POR. GH adjuvant therapy to ART is considered a promising drug. However, GH complications are not well studied. Methods Between 2021 to 2022. A prospective randomized control study, in which patients were divided into two groups, a study and a control group. Study group will receive an ICSI cycle with GH supplementation and control group. Results 37 patients per group were included. Their mean age was 29.74± 5.88 years. The mean duration of infertility is also similar between the GH group (4.81 ± 2.16) and the control group (4.73 ± 2) with no significant difference between the groups (p = 0.86721). The average systolic blood pressure for the study group and the control group were 113 ± 20 ( 88 -135) and 110 ± 22 ( 87-130) mmHg respectively with no statistical significant difference ( p = 0.7412). The average random blood sugar mg/dl for the study group and the control group were 123±20 (90-140) and 119 ±24 ( 87-138) with no statistical significant different ( P= 0.6539). (Table 2) There were no cases with leg edema, added pain or change in overall features. Conclusion GH may have a positive role in POR undergoing ovarian stimulation. In addition, no sinister side effects of GH have been reported. | ||||
Keywords | ||||
GH; Complications; POR; infertility | ||||
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