ANTI-CANCER MEDICINS (CLASSIFICATION AND MECHANISMS OF ACTION) | ||||
| Egyptian Dental Journal | ||||
| Volume 70, Issue 1 - Serial Number 3, January 2024, Page 147-164 PDF (2.25 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2023.234480.2708 | ||||
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| Authors | ||||
Ahmed Mohammad Hussein   1; Khaled Abd-Elsalam Hussein 2; Hamzah Ali Babkair 2; Mohamed Badawy 3
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| 1Oral and Maxillofacial Pathology Department, Faculty of Dentistry, Assiut University, Assiut, Egypt | ||||
| 2Division of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diagnostic Sciences Department, College of Dentistry, Taibah University, Madina, Saudi Arabia | ||||
| 3Oral Biology Department, Faculty of Dentistry, Assiut University, Assiut, Egypt | ||||
| Abstract | ||||
| Cancer is one of the chief dying cause in the world, killing roughly 3500 people/million each year. Malignancy is motivated by genetic defect in the cellular material in view of ecological or hereditary roads. Surgical operation and radiation are used as early intervention helped for regional and non-metastatic foreign mass, else are deficient in the neoplasms have diffused through the body. Usage of medications is one of the current choice for curing malignant tissues, since they are able to reach all human organs via the bloodstream. Anti-cancer medicines mainly include chemotherapy, immunotherapy, targeted therapy, and hormonal therapy; may be serviced before or after surgery or radiotherapy. Many kinds of anti-neoplastic compounds are valued alone or in fusion with other treatments. These agents are varying in their chemical forms, their prescription and doses, how beneficial they are in healing diverse sorts of lesions, and their undesirable effects. Medicaments of anti-malignancy are not easily categorized into groups. Several classifications have been proposed and none is totally satisfactory. Thus, drugs have been typed according to their chemical composition, presumed mechanisms of action, and cytotoxic activity to the cell cycle. Each categorizing has merits, but the fact that there are so many ways of grading these agents reflect the disparate origin of anti-cancer remedies, knowledge of their actions, and bases of tumor selectivity. | ||||
| Keywords | ||||
| Cancer; Chemotherapy; Immunotherapy; Targeted Therapy; Hormone Therapy | ||||
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