Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus
gamal, S., Sabry, M., yousef, D. (2024). Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus. EKB Journal Management System, 70(1), 179-187. doi: 10.21608/edj.2023.239162.2727
sherouk mohamed gamal; Marwa Sabry; doaa ahmed yousef. "Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus". EKB Journal Management System, 70, 1, 2024, 179-187. doi: 10.21608/edj.2023.239162.2727
gamal, S., Sabry, M., yousef, D. (2024). 'Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus', EKB Journal Management System, 70(1), pp. 179-187. doi: 10.21608/edj.2023.239162.2727
gamal, S., Sabry, M., yousef, D. Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus. EKB Journal Management System, 2024; 70(1): 179-187. doi: 10.21608/edj.2023.239162.2727

Evaluation of the Efficacy of Topical Propolis versus Mucoadhesive Mycophenolate Mofetil (MMF) in the Management of Symptomatic Oral Lichen Planus

Egyptian Dental Journal
Volume 70, Issue 1 - Serial Number 3, January 2024, Page 179-187  XML PDF (1004.64 K)
Document Type: Original Article
DOI: 10.21608/edj.2023.239162.2727
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Authors
sherouk mohamed gamal email orcid 1; Marwa Sabryorcid 2; doaa ahmed youseforcid 3
1Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dentistry, Tanta University
2Lecturer of Pedodontics Department, Faculty of Dentistry, KFS University
3Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Tanta University
Abstract
Aim: To assess the potential impacts of propolis and mucoadhesive mycophenolate mofetil (MMF) on oral lichen planus.
Methodology: The research was performed on 30 individuals suffering from atrophic-erosive oral lichen-planus. And they were allocated into three groups; Group Ӏ: were managed with propolis 5% gel, Group ӀӀ: were managed with Mycophenolate mofetil (MMF) 2% mucoadhesive and Group ӀӀӀ (control group): were managed with triamcinolone acetonide 0.1%. The clinical progress was evaluated utilizing the Visual Analog Scale (VAS) for pain intensity and MOMI scale. The clinical parameters were recorded at the baseline and then every two weeks for two months.
Results: A substantial enhancement existed in all clinical results throughout the follow-up period when compared to the baseline (P <0.05). There was non-significant variation among the studies groups at the end of the eight’s week regarding VAS and MOMI scale (P˃0.05).
Conclusions: Propolis and MMF might be utilized as alternative treatment for the management of oral lichen-planus.
Keywords
Oral lichen planus; mucoadhesive mycophenolate mofetil; propolis
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