DETERMINATION OF THE FLAVONOIDS OF BROCCHIA CINEREA FROM ALGERIA | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 10, Volume 47, Issue 1, June 2024, Page 169-177 PDF (604.56 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.2023.243683.1954 | ||||
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| Authors | ||||
Mohammed Tahar Ben Moussa  1; Said Nadji2; Abdelhakim Bounab3; Youcef Hadef4
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| 1Department of pharmacy, University of Batna2 | ||||
| 2Laboratory of toxicology, University hospital of Batna | ||||
| 3Laboratory of mineral chemistry, Faculty of pharmacy, University of Algiers | ||||
| 4Laboratory of Analytical chemistry, Departement of pharmacy, Faculty of Medicine, University of Annaba | ||||
| Abstract | ||||
| Brocchia cinerea is a plant from North Africa, member of the Asteraceae family; the plant is highly used in Algeria to relieve some ailments. Various classes of compounds are naturally encountered in the plant as tanins, polyphenols and flavonoids, these compounds could play a primordial pharmacological role giving to the plant its therapeutic proprieties. In the current study, the plant's flowers were collected from two sites in Algeria, in order to extract the flavonoids; which were subsequently identified using HPLC-DAD-MS. The results of the analysis identified 10 flavonoids: 2,2':3',2'':3'',2'''-Quaternaphthalene-1,1',1'',1''',4,4',4'',4'''-octone, Quercetin 3-O-beta-D-galactopyranoside, Hesperidin, Sakuranin, Quercetin-4'-glucoside, Flavone, 2',5,5',6-tetrahydroxy-3,4',7-trimethoxy-, tetraacetate, 6,11,12,17-Tetraacetoxy-5,18-trinaphthylenedione, Isoorientin, Luteolin, 4H-1-Benzopyran-4-one, 5,6-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-. Multivariate statistics have been conducted in order to elucidate the variabilities. Close chemical patterns were noted between the samples, with small inter-region and inter-samples variabilities, except for one sample that standed as an outlier presenting different flavonoid levels pattern. This is crucial to understand the variabilities in the pharmacological proprieties of Brocchia. | ||||
| Keywords | ||||
| Flavonoids; Brocchia cinerea; Asteraceae | ||||
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