Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion
Sibai, H., Nossair, W., Abdelghane, N., Diab, W. (2024). Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion. EKB Journal Management System, 30(1.7), 3909-3922. doi: 10.21608/zumj.2023.255723.3050
Hoda Sibai; Wael Sabry Nossair; Najma Amhimmid Abuzid Abdelghane; Wafaa Mohamed Diab. "Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion". EKB Journal Management System, 30, 1.7, 2024, 3909-3922. doi: 10.21608/zumj.2023.255723.3050
Sibai, H., Nossair, W., Abdelghane, N., Diab, W. (2024). 'Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion', EKB Journal Management System, 30(1.7), pp. 3909-3922. doi: 10.21608/zumj.2023.255723.3050
Sibai, H., Nossair, W., Abdelghane, N., Diab, W. Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion. EKB Journal Management System, 2024; 30(1.7): 3909-3922. doi: 10.21608/zumj.2023.255723.3050

Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion

Zagazig University Medical Journal
Article 20, Volume 30, Issue 1.7, October 2024, Page 3909-3922  XML PDF (903.63 K)
Document Type: Original Article
DOI: 10.21608/zumj.2023.255723.3050
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Authors
Hoda Sibai1; Wael Sabry Nossair2; Najma Amhimmid Abuzid Abdelghane email 3; Wafaa Mohamed Diab4
1Assistant Professor of Obstetrics and Gynecology, Faculty of Medicine- Zagazig University, Egypt
2Professor of Obstetrics and Gynecology Gynecology Faculty of Medicine - Zagazig University
3M.B.B.Ch., Faculty of Medicine, Sebha University, Libya
4Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Egypt
Abstract
Background: Misoprostol is a successful abortion medication when administered vaginally, orally, or sublingually. we aimed for comparing safety in addition to efficacy of different regimens for missed abortion termination of through using sublingual misoprostol, vaginal misoprostol alone, versus sublingual misoprostol, vaginal misoprostol with insertion of cervical Foley’s catheter.

Subjects and methods: This prospective randomized controlled trial included 172 pregnant women. Group A (Sublingual group) that subdivided into 2 subgroups: I (A): 43 patients to whom misoprostol tablet was given sublingually every 4 hours up to 6 doses per day, I (B):43 patients to whom misoprostol tablet was given sublingually every four hours up to six doses per day plus Foley’s catheter (18fr) insertion through cervix, Group B (Local “vaginal” group): that subdivided into two subgroups; II (A): 43 patients to whom misoprostol tablet was given vaginally every four hours up to six doses per day, II (B): 43 patients to whom misoprostol tablet was given vaginally every four hours up to six doses per day plus Foley’s catheter (18Fr) insertion through cervix.

Results: Sublingual misoprostol plus cervical Foley’s cathe-ter insertion is associated with higher success rate and least induction to abortion interval; length of hospitalization, number/total of doses of misoprostol needed for terminating pregnancy and need for hysterotomy.

Conclusion: sublingual misoprostol plus cervical Foley’s catheter insertion isbest option for management of pregnant women with missed abortion
Keywords
Sublingual Misoprostol; Local Misoprostol; Foleys Catheter; Cervical Insertion; Missed Abortion
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