Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol
El-Nassery, N., Shohayeb, A., Gamea, M., Maged, A., Soliman, M. (2023). Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol. EKB Journal Management System, 27(6), 99-105. doi: 10.21608/egyfs.2023.333784
Noura El-Nassery; Amal Shohayeb; Mostafa Gamea; Ahmed M Maged; Mahmoud Soliman. "Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol". EKB Journal Management System, 27, 6, 2023, 99-105. doi: 10.21608/egyfs.2023.333784
El-Nassery, N., Shohayeb, A., Gamea, M., Maged, A., Soliman, M. (2023). 'Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol', EKB Journal Management System, 27(6), pp. 99-105. doi: 10.21608/egyfs.2023.333784
El-Nassery, N., Shohayeb, A., Gamea, M., Maged, A., Soliman, M. Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol. EKB Journal Management System, 2023; 27(6): 99-105. doi: 10.21608/egyfs.2023.333784

Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol

The Egyptian Journal of Fertility of Sterility
Article 12, Volume 27, Issue 6 - Serial Number 11106352, November 2023, Page 99-105  XML PDF (3.29 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2023.333784
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Authors
Noura El-Nassery email 1; Amal Shohayeb2; Mostafa Gamea2; Ahmed M Maged2; Mahmoud Soliman2
1Obstetrics and Gynecology Department, Cairo University, Egypt
2Obstetrics and Gynecology Department, Cairo University, Cairo, Egypt
Abstract
Objective : to explore the benefits of the E2 priming during the luteal phase in women with poor ovarian response (POR) undergoing IVF cycles using the GnRH antagonist protocol.   
Methods : This randomized controlled study conducted on 100 POR underwent ICSI trial using GnRH antagonist protocol assigned to 1 group of 2. Group I included 50 women received oral E2 valerate 4 mg/day started on luteal day 21 and continued up to the 1st day of the cycle group II included 50 control women who did not receive estrogen priming. The main outcome parameter was the number of MII oocytes. Other outcomes included implantation, chemical pregnancy and clinical pregnancy rates.   
Results: No statistically significant difference between women in the estrogen priming group and other women regarding the retrieved oocytes number and quality, implantation, clinical pregnancy, or chemical pregnancy rates.  
Conclusion: estrogen priming did not increase the number of MII retrieved ova in POR.  
Keywords
Keywords: Estrogen priming; Poor ovarian responders; clinical pregnancy rate; IVF
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