Effect of quetiapine on arterial oxygen saturation on head trauma patients | ||||
Minia Journal of Medical Research | ||||
Articles in Press, Accepted Manuscript, Available Online from 08 January 2024 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2024.260037.1599 | ||||
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Authors | ||||
Ahmed Ali El-Sayed 1; ali taha 2; Khaled Ahmed Abdou1 | ||||
1Anesthesiology and ICU, faculty of medicine, Minia university, Minia, Minia | ||||
2Anesthesia,Medicine,Minia University | ||||
Abstract | ||||
ABSTRACT Background: Traumatic brain injury (TBI) is considered a major global public health epidemic, economic and social issue as it is the main cause of death and disability in most countries. Aim and objectives: To assess and evaluate the efficacy and safety of Quetiapine in the management of agitated behaviors following traumatic brain injury (TBI) and its effect on arterial oxygen saturation Patient and methods: This prospective randomized controlled study conducted on 40 adult patients (divided into 2 equal groups, 20 cases each) aged 18-60 years old with isolated moderate TBI in trauma ICU of Minia University Hospital (MUH) starting from July 15, 2022. Results: There was a substantial variation between the two studied groups as regard arterial oxygen saturation readings which was significantly higher in group Q compared to group C in the 7th and 8th days. Conclusion: Quetiapine was safe and effective in the management of agitated behaviors following traumatic brain injury (TBI) and improvement of arterial oxygen saturation. | ||||
Keywords | ||||
TBI; Psychosis; Delirium; SO2 | ||||
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