The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study
AbdelHaleem, A., Behery, A., Ibrahim, R., Abdel Hafez, S., Ali, A. (2024). The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study. EKB Journal Management System, (), -. doi: 10.21608/mjmr.2023.249344.1542
Aliaa Hamdy AbdelHaleem; Amira Fathy Behery; Randa Ahmed Ibrahim; sara Mohamed Naguib Abdel Hafez; Azza Hussein Ali. "The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study". EKB Journal Management System, , , 2024, -. doi: 10.21608/mjmr.2023.249344.1542
AbdelHaleem, A., Behery, A., Ibrahim, R., Abdel Hafez, S., Ali, A. (2024). 'The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study', EKB Journal Management System, (), pp. -. doi: 10.21608/mjmr.2023.249344.1542
AbdelHaleem, A., Behery, A., Ibrahim, R., Abdel Hafez, S., Ali, A. The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study. EKB Journal Management System, 2024; (): -. doi: 10.21608/mjmr.2023.249344.1542

The possible effects of Zinc sulfate on adult rat olfactory mucosa. A histological study

Minia Journal of Medical Research
Articles in Press, Accepted Manuscript, Available Online from 08 January 2024  XML
Document Type: Original Article
DOI: 10.21608/mjmr.2023.249344.1542
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Authors
Aliaa Hamdy AbdelHaleem email 1; Amira Fathy Behery2; Randa Ahmed Ibrahim3; sara Mohamed Naguib Abdel Hafezorcid 1; Azza Hussein Ali4
1Histology and Cell biology Department, faculty of Medicine, Minia University, Minia, Egypt
2Department of Histology and Cell Biology, Faculty of Medicine, Minia University, Minia, Egypt
3Histology and cell biology, faculty of medicine, Minia University, Minia., Egypt
4Histology and cell biology department Faculty of medicine Minia university, Minia, Egypt
Abstract
Abstract:

Background: Zinc (Zn) is a well-known trace element that helps regulate a variety of physiological activities. Zinc sulfate (ZnS) is an inorganic chemical, commonly used in zinc insufficiency therapy. Previously oral Zinc supplementation was found to help shorten length of the common cold; however, intranasal Zinc use has been linked to anosmia, or loss of smell, in humans.

Aims of work: This work aims to assess possible effects of ZnS induced toxicity on adult male albino rat olfactory mucosal histological structure.

Methods: Twenty rats were equally allocated into two groups: Control group (C- group) and Zinc sulfate (ZnS) group (given intranasally as 10% ZnS solution).Olfactory mucosa was processed for histological study.

Results: ZnS group showed marked structural alterations in olfactory mucosa in the form of thinning, desquamation of olfactory epithelium and degeneration of both nerve bundles Bowmans glands in the lamina propria.

Conclusion: Zinc sulfate produced destruction of olfactory mucosa in adult male albino rats.

Keywords: Zinc, anosmia, olfactory
Keywords
Zinc; anosmia; olfactory
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