Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.
Abdalla, S., Elbaz, A., Emara, R. (2024). Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.. EKB Journal Management System, 6(1), 51-59. doi: 10.21608/adjc.2023.211035.1310
Samah Sobhie Abdalla; Alaa Abdelsalam Elbaz; Radwa Sameh Emara. "Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.". EKB Journal Management System, 6, 1, 2024, 51-59. doi: 10.21608/adjc.2023.211035.1310
Abdalla, S., Elbaz, A., Emara, R. (2024). 'Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.', EKB Journal Management System, 6(1), pp. 51-59. doi: 10.21608/adjc.2023.211035.1310
Abdalla, S., Elbaz, A., Emara, R. Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.. EKB Journal Management System, 2024; 6(1): 51-59. doi: 10.21608/adjc.2023.211035.1310

Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Postoperative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial.

Advanced Dental Journal
Volume 6, Issue 1, January 2024, Page 51-59  XML PDF (346.88 K)
Document Type: Original Article
DOI: 10.21608/adjc.2023.211035.1310
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Authors
Samah Sobhie Abdalla email 1; Alaa Abdelsalam Elbaz email orcid 2; Radwa Sameh Emara email 2
1Endodontic Dentistry, Faculty of Dentistry, Cairo University, Egypt
2Endodontic Department, Faculty of Dentistry, Cairo University, Egypt
Abstract
Introduction: The purpose of this study was to compare postoperative pain and the amount of analgesic intake after administration of a preoperative single dose of sodium ibuprofen versus placebo in lower molar teeth with symptomatic irreversible pulpitis (SIP)
Methods: Fifty patients were randomly divided into two groups, in the experimental group, patients were given one tablet of sodium ibuprofen (NUROFEN) 256 mg, 30 minutes before endodontic treatment, and control group patients received one placebo tablet, 30 minutes before endodontic treatment. Participants rated their pain using a visual analogue pain scale (VAS) preoperatively and at 5-time points: immediately post-operative, 6, 12, 24, and 48 hours and the number of analgesic tablets taken up to 48 hours postoperatively.
Results: Baseline characteristics of both groups showed non-significant differences (P >0.05). The sodium ibuprofen group revealed statistically significantly less postoperative pain levels at 6, 12, and 24 hours, respectively, and was associated with significantly less postoperative pain incidence at 6 and 12 hours (p<0.05). No patient reported analgesic intake
Conclusions: Within the study limitations, single preoperative oral dose of Nurofen proved to be an effective premedication that reduced post-operative pain for patients diagnosed with symptomatic irreversible pulpitis of mandibular molars.
Keywords
symptomatic irreversible pulpitis; mandibular molars; post-operative pain; sodium ibuprofen; randomized controlled trial
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