Perforated Meckel’s diverticulum in neonates: a report of six cases and systematic review of the literature | ||||
| Annals of Pediatric Surgery | ||||
| Volume 18, Issue 1, January 2022 PDF (904.52 K) | ||||
| DOI: 10.1186/s43159-021-00154-z | ||||
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| Authors | ||||
Naeem Liaqat   ; Anies Mahomed; Sajid Iqbal Nayyar; Nadeem Akhtar; Sajjad Ali; Naveed Haider
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| Abstract | ||||
| Background Perforation of Meckel Diverticulum (MD) is a rare cause of pneumoperitoneum in neonates. We hereby report six cases of perforation of MD in neonates, with addition of 53 cases from systematic review of the literature. A systematic review was performed using Mesh terms “Neonate, Meckel Diverticulum, Perforation, Pneumoperitoneum.” All reports of perforated MD in the English literature were identified. Details of our 6 cases were analyzed in similar fashion. Results A total of 3027 manuscripts were screened and 59 cases including 6 of our own were identified. The vast majority (78%) were female. Fifty patients (84.7%) presented in the newborn period. Half of the cases (52.5%) had associated anomalies and 13 neonates (22%) required oxygen supplementation including CPAP or ventilatory support before surgery. In 73% of the cases, a resection of gut was undertaken. Histopathological assessment in 44 cases (74.6%) revealed no ectopic gastric mucosa. Three cases demised prior to treatment. The outcome in the vast majority was excellent with 84.7% surviving and discharged well. Conclusion Perforated MD is an unusual cause of a pneumoperitoneum in the newborns. Diagnosis is established at laparotomy and it rare to find ectopic mucosa histopathologically. The overall outcome is excellent. | ||||
| Keywords | ||||
| Neonate; Meckel diverticulum; Neonatal; pneumoperitoneum | ||||
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