Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study
Nassereldine, H., Hajj-Ali, A., Hassanieh, J., Hamideh, D., Jaafar, R., Akel, S., Zaghal, A. (2022). Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study. EKB Journal Management System, 18(1), -. doi: 10.1186/s43159-022-00227-7
Hasan Nassereldine; Adel Hajj-Ali; Joelle Hassanieh; Dima Hamideh; Rola F. Jaafar; Samir Akel; Ahmad Zaghal. "Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study". EKB Journal Management System, 18, 1, 2022, -. doi: 10.1186/s43159-022-00227-7
Nassereldine, H., Hajj-Ali, A., Hassanieh, J., Hamideh, D., Jaafar, R., Akel, S., Zaghal, A. (2022). 'Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study', EKB Journal Management System, 18(1), pp. -. doi: 10.1186/s43159-022-00227-7
Nassereldine, H., Hajj-Ali, A., Hassanieh, J., Hamideh, D., Jaafar, R., Akel, S., Zaghal, A. Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study. EKB Journal Management System, 2022; 18(1): -. doi: 10.1186/s43159-022-00227-7

Catheter-related atrial thrombosis: prevalence and risk factors in the pediatric age group—a retrospective study

Annals of Pediatric Surgery
Volume 18, Issue 1, January 2022  XML PDF (1 MB)
DOI: 10.1186/s43159-022-00227-7
View on SCiNiTO View on SCiNiTO
Authors
Hasan Nassereldine; Adel Hajj-Ali; Joelle Hassanieh; Dima Hamideh; Rola F. Jaafar; Samir Akel; Ahmad Zaghal email orcid
Abstract
Background
Catheter-related right atrial thrombosis (CRAT) is an under-studied complication of a long-term implantable venous access devices (IVAD), particularly in children with incidence rates extrapolated from the adult literature ranging between 2 and 29%. This is a single-center retrospective review of electronic medical records of children who underwent insertion of IVADs and had at least one echocardiogram performed prior to catheter removal between 2008 and 2018. Data collection included demographic information, development of CRAT, systemic infection, and administration of thrombogenic chemotherapeutic agents. We identified six patients who developed CRAT and compared them to 120 control patients. We also performed a detailed chart review for the patients who developed CRAT. Data was entered and analyzed using SPSS.
Results
A total of 764 patients underwent IVAD placement between 2008 and 2018. Six (0.79%) patients developed CRAT, and 120 patients were identified as controls that match the CRAT patients based on definitive criteria that include age, gender, chemotherapy type, steroid therapy, reason of line insertion, site of catheter insertion, tip-location at insertion, and history of systemic infections. In the CRAT group, 3 (50%) patients had their catheter tips placed in the superior vena cava-right atrial junction and 3 (50%) in the right atrium, whereas in the control group, all patients had their catheter tips placed in the superior vena cava-right atrial junction (=0.000). Five (83.3%) patients in the CRAT group received L-asparaginase as compared to 75 (62.5%) patients in the control group (=0.301). In the CRAT group, all patients had a history of systemic infection compared to 47 (39.2%) in the control group (=0.180).
Conclusion
We identified 6 (0.79%) children with CRAT. Catheter-tip location within the right atrium is a potential risk factor for CRAT development in children.
Keywords
Central venous catheter; Venous access; Central venous catheter thrombosis; Atrial thrombosis
Statistics
Article View: 22
PDF Download: 20