Efficacy of Lifestyle Interventions on Body Weight and Elevated Liver Enzymes among Patients with Non-Alcoholic Fatty-Liver Disease | ||||
| International Egyptian Journal of Nursing Sciences and Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 13 January 2024 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejnsr.2023.243166.1324 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Engy EE El Doushy  1; Amal A. Elabassy2; Hemat Mostafa Amer3; Elham S. Elzyeny4
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| 1Medical surgical Nursing Faculty of Nursing- Menoufia University Egypt | ||||
| 2community health nursing faculty of nursing-Menoufia university- Egypt | ||||
| 3community health nursing faculty of nursing Menoufia University-Egypt | ||||
| 4Lecturer of Community health nursing, Faculty of Nursing/ Menoufia University, Egypt | ||||
| Abstract | ||||
| Non-alcoholic fatty-liver disease is called the silent epidemic mortality for young adults. Lifestyle interventions including healthy dietary, physical activity and exercise program remain the cornerstone treatment approach for this disease. Aim: To examine the effect of lifestyle interventions on bodyweight and elevated liver-enzymes among patients with non-alcoholic fatty-liver disease. Methods: Design: A qausi-experimental design. Subjects: A simple random sample of 200 patients with non-alcoholic fatty-liver. Sitting: Outpatients' clinics of Teaching Hospital and the National Liver Institute, Menoufia Governorate, Egypt. Instruments: Five tools: Structured Interview questionnaire, Reported patient's dietary practices questionnaire, The Nordic Physical Activity and Exercise questionnaire-Short, The 24-Hours dietary recall, and Bio-physiological measurements' tool. Results: There were significant post-intervention improvements in the total mean scores among study group regarding healthy dietary practices as it increased from 37.8±4.6 on pre-intervention to 49.6±5.8 post, body weight measures significantly decreased from 80.0±16.7 pre- to 73.4±18.3 post- and body mass index decreased from 30.1±12.2 pre- to 27.6±13.1 post. Besides, liver enzymes' total post-intervention mean scores for study group significantly reduced to 43.5±21.9 and 36.9±11.7 compared to control's 68.2±12.4 and 54.4±12.0, respectively for Aspartate aminotransferase and Alanine aminotransferase, likewise physical exercise practices' total post-intervention mean scores were statistically significant (p<0.05) . Conclusion: Lifestyle interventions; practicing of physical exercise and healthy nutrition, proved to be effective in gradual reduction of both bodyweight and liver-enzymes. Recommendations: Healthy lifestyle modifications should be considered as an initial step for both prevention and management of Non-alcoholic fatty-liver disease. | ||||
| Keywords | ||||
| Keywords: Body weight; Lifestyle Interventions; Liver Enzymes and Non-Alcoholic-Fatty Liver Disease | ||||
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