The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome
Bendary, A., Shehab, M., Gamal, A., El-Emary, M., Shawky, M. (2025). The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome. EKB Journal Management System, 42(2), 21-34. doi: 10.21608/bmfj.2023.240482.1911
Ahmed Bendary; Mustafa Shehab; Abdelrahman Gamal; Metwally Hasan El-Emary; Mahmoud Shawky. "The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome". EKB Journal Management System, 42, 2, 2025, 21-34. doi: 10.21608/bmfj.2023.240482.1911
Bendary, A., Shehab, M., Gamal, A., El-Emary, M., Shawky, M. (2025). 'The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome', EKB Journal Management System, 42(2), pp. 21-34. doi: 10.21608/bmfj.2023.240482.1911
Bendary, A., Shehab, M., Gamal, A., El-Emary, M., Shawky, M. The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome. EKB Journal Management System, 2025; 42(2): 21-34. doi: 10.21608/bmfj.2023.240482.1911

The Impact of Coronary Slow Flow Phenomenon on Diastolic Function Trajectory in Patients with Non-ST Segment Elevation Acute Coronary Syndrome

Benha Medical Journal
Article 3, Volume 42, Issue 2, February 2025, Page 21-34  XML PDF (582.04 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2023.240482.1911
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Authors
Ahmed Bendaryorcid 1; Mustafa Shehab email 2; Abdelrahman Gamal3; Metwally Hasan El-Emary4; Mahmoud Shawky5
1Cardiology department, Benha faculty of medicine, Benha University
2Department of Cardiology Faculty of Medicine, Benha University
3Consultant cardiology, National Heart Institute
4Cardiology department,Benha university
5Cardiology Department, Faculty of Medicine, Benha University
Abstract
Background: Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) patients often present with complex cardiac pathophysiology, including coronary slow flow phenomenon (CSFP) and diastolic dysfunction (DD). This study aimed to better understand the short-term alterations and indicators of improved diastolic function in CSFP patients presenting with NSTEMI. Methods: This prospective research was conducted on 100 NSTE-ACS patients undergoing coronary angiography. Echocardiographic measures were employed to determine diastolic function, and the TIMI frame count approach was employed to determine the presence of CSFP. At the start of the study and after three months, clinical and angiographic data were gathered. Results: The mean age of the studied patients was 46 ±4 years. Significant improvements were noted in several diastolic function parameters at three months. At three months, there were significantly lower percentages of average E/Em > 14 (2% vs. 16%, P < 0.001), LAVI > 34 mL/m2 (46% vs. 76%, P < 0.001), lateral Em < 10 (61% vs. 76%, P < 0.001), and TR velocity (41% vs. 76%, P < 0.001) compared to baseline. Kaplan Meier analysis was done to calculate MACE-free survival. It showed that at 1.5 months, the MACE-free survival was 97.8% and 92.7% in those with improved and non-improved diastolic dysfunction, respectively. Conclusion: Our study shows the positive impact of diagnosing and managing CSFP in NSTE-ACS patients, as it may lead to improved diastolic function over a relatively short period.
Keywords
NSTE-ACS; Coronary Slow Flow Phenomenon; Diastolic Function; Major Adverse Cardiac Events; Echocardiography
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