Developing Biodegradable Polymeric Composite for Nails Manufacturing of Bone Fracture Fixation | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 67, Issue 13, December 2024, Page 349-359 PDF (719.84 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2024.257443.9038 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed Mohamed Yousry  1; Hassan M. M. Mustafa 2; Wael Abdelmoez3; Mohamed Tarek El-Wakad4; Mohamed S. Abdo 5
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| 1Biomedical Engineering Department, Faculty of Engineering, Helwan University, Helwan, Egypt | ||||
| 2Mechanical Engineering Department, Engineering and Renewable Energy Research Institute, National Research Centre, Giza, Egypt. | ||||
| 3Chemical Engineering Department, Faculty of Engineering, Minia University, Minia, Egypt | ||||
| 4Faculty of Engineering and Technology, Future University Egypt, Fifth settlement, Cairo, Egypt | ||||
| 5Biomedical Engineering Department, Faculty of Engineering, Minia University, Minia, Egypt. | ||||
| Abstract | ||||
| Biodegradable implants, a popular research focus, aim to address issues associated with traditional titanium and stainless-steel implants, including bone abnormalities and the need for additional surgeries. Our novel protein-based thermoplastic material, derived from blood albumin, serves as a promising biodegradable implant. Despite inherent weak mechanical properties in biodegradable materials, we enhance our biopolymer by incorporating reinforcing components like Nanoclay, PVA, and PLA. Three composite groups were tested, and various fabrication techniques were explored, revealing that dry casting with pure protein or 20% nanoclay concentration yields the best mechanical properties for bone fixation plates. The tensile strength of the dry casting plate is 8.3 MPa for pure protein. Our results indicate that this novel protein-based material, particularly with dry casting, presents a promising alternative to traditional fixation plate materials for pediatric or maxilla bone fractures with lower load requirements. | ||||
| Keywords | ||||
| Natural biomaterials; protein-based biomaterials; biodegradable implants | ||||
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