Comparison between dexmedetomidine and neostigmine as an adjuvant to bupivacaine and lidocaine in peribulbar block for cataract surgery. | ||||
Minia Journal of Medical Research | ||||
Articles in Press, Accepted Manuscript, Available Online from 05 February 2024 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2024.262020.1621 | ||||
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Authors | ||||
Samar Ali Mohamed 1; hany kamal2; Ahmed Abdelghany3; Mostafa Mahmoud Ali4 | ||||
1Anesthesia and Intensive care department,Faculty of Medicine,El_Minia University | ||||
2Anesthesiology and Intensive care department,Faculty of Medicine,Minia University. | ||||
3Ophthalmology department, Faculty of Medicine, Minia University. | ||||
4Department of Anesthesiology and Intensive department, Faculty of Medicine, Minia University, Egypt | ||||
Abstract | ||||
Abstract: Background: Local anesthetics are often injected into the peribulbar region. However, using just local anesthetics is associated with delayed globe akinesia onset, shorter duration of pain relief, and frequent block reapplication requirements. In comparison to a mix of local anesthetics. This research aimed to evaluate the effects of adding dexmedetomidine and neostigmine to local anesthetic in peribulbar block on hemodynamic of patients and quality of the block. Study design: A study that is prospective, randomized, and double-blinded. Methods: Sixty patients were a part of the present study's cohort at Minia University Hospital. A control group had just a local anaesthetic combination; the other two groups were of similar size. Patients were randomly assigned to these groups. In the group given dexmedetomidine, twenty patients were given a dosage of 25µg of the drug in addition to a mix of local anesthetics. Twenty individuals had a combination of local anesthetics and 0.4 mg of neostigmine as part of the Neostigmine group. Results: The three groups showed negligible disparities in terms of hemodynamic metrics. The Dexmedetomidine group exhibited a much faster onset and longer duration of sensory and motor block in comparison to the other groups. The group that received dexmedetomidine experienced considerably better levels of satisfaction among both patients and surgeons. Conclusion: This research revealed that adding dexmedetomidine or neostigmine to the local anesthetic mixture improved the quality of the block and patients and surgeon satisfaction with minimal hemodynamic effects and without changes in the incidence of side effects. | ||||
Keywords | ||||
Dexmedetomidine; Neostigmine; Peribulbar; anesthesia | ||||
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