Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection
Salem, A., Gaber, N., Mohamed, E., Morgan, D. (2024). Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection. EKB Journal Management System, 5(1), 92-105. doi: 10.21608/ejmr.2023.216582.1402
Aida Mohamed Said Salem; Nada Soliman Gaber; Eman Hamdy Mohamed; Dalia Saber Morgan. "Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection". EKB Journal Management System, 5, 1, 2024, 92-105. doi: 10.21608/ejmr.2023.216582.1402
Salem, A., Gaber, N., Mohamed, E., Morgan, D. (2024). 'Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection', EKB Journal Management System, 5(1), pp. 92-105. doi: 10.21608/ejmr.2023.216582.1402
Salem, A., Gaber, N., Mohamed, E., Morgan, D. Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection. EKB Journal Management System, 2024; 5(1): 92-105. doi: 10.21608/ejmr.2023.216582.1402

Short-Term Outcomes in Children with multisystem inflammatory syndrome associated with SARS-COV2 Infection

Egyptian Journal of Medical Research
Volume 5, Issue 1, January 2024, Page 92-105  XML PDF (605.59 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2023.216582.1402
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Authors
Aida Mohamed Said Salem1; Nada Soliman Gaber email 1; Eman Hamdy Mohamed2; Dalia Saber Morgan1
1Pediatrics Department, Faculty of Medicine, Beni-Suef University, Egypt
2Clinical pathology department, Faculty of Medicine, Beni-Suef University, Egypt
Abstract
Background and aims: Signs of inflammation and multi organ dysfunction describe a novel clinical disorder called multisystem inflammatory syndrome in children (MIS-C), which is caused by the cytokine storm correlated with SARS-CoV-2. This study aimed to follow up with children with MIS- C correlated with SARS-COV2 infection to determine any sequalae or delayed manifestation of MIS-C. Methods: Children less than 18 years old with a diagnosis of MIS-C were included in this prospective research at the Beni-Suef University Hospital. Comparative analyses of admission and po st discharge clinical and laboratory parameters were performed. Results: Fifty-three children were involved in the research from March 2022 to July 2022 with a mean age of 5.08 ±4.05 years. Fourteen o f the youngsters already had chronic systemic comorbidity. The presence of fever was observed in every case. The hematological (92.45%), GIT, and neurological (56.6%) systems were the most affected. Mo rtality is significantly higher among children with young age, chronic illness, and MIS- C clinical presentation overlapping with COVID-19 infection. Lymphopenia and thrombocytopenia were more common among dead than survivor patients. Conclusions: The prognosis is good for children with no underlying medical conditions. Low lymp hocyte counts and elevated troponin levels may be unfavorable indicators of survival. Positive follow-up results in coronary care were reported.
Keywords
Short outcome; Multisystem inflammatory syndrome in children; COVID-19; Kawasaki disease
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