BIOCHEMICAL AND BIOLOGICAL STUDIES ON ZINC OXIDE NANOPARTICLES | ||||
Menoufia Journal of Agricultural Biotechnology | ||||
Article 3, Volume 9, Issue 1, January 2024, Page 1-10 PDF (727.33 K) | ||||
Document Type: original papers | ||||
DOI: 10.21608/mjab.2024.258618.1015 | ||||
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Authors | ||||
mostafa hamam1; samir mohamed2; salah mansour2; reda rashed ![]() | ||||
1Faculty Agricultural-Biochemistry Dep .-Mynofia University | ||||
2Biochemistry Department, Faculty of Agriculture, Menofia University, Shibin El-Kom, Egypt | ||||
Abstract | ||||
The current study endeavors to examine the synthesis of zinc oxide nanoparticles, which find utility in various domains such as biomedical, electrochemistry, and catalysis. The zinc oxide nanoparticles were fabricated through sol gel techniques utilizing zinc acetate and zinc sulfate as precursors. Subsequently, these nanoparticles were subjected to characterization using X-ray diffraction, FTIR analysis, and TEM analysis. Furthermore, the antioxidant activity of the zinc oxide nanoparticles was evaluated employing the DPPH assay, while their antimicrobial efficacy against Gram positive and Gram negative bacteria was also investigated. Additionally, the toxicity of the zinc oxide nanoparticles on adult male Westar rats was assessed by assessing liver function, kidney function, lipid profile, and blood sugar level. The outcomes of the study revealed a significant rise in all liver and kidney functions, glucose, cholesterol, low-density cholesterol, and triglycerides, in comparison to the negative control. However, the high-density cholesterol exhibited a decrease relative to the negative control | ||||
Keywords | ||||
Zinc oxide nanoparticles; toxicity; antimicrobial; antioxidant | ||||
Supplementary Files
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