Characteristics and outcome of children with unilateral multicystic dysplastic kidney disease in Upper Egypt | ||||
| Sohag Medical Journal | ||||
| Volume 28, Issue 2, 2024, Page 28-35 PDF (857.14 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/smj.2024.261104.1441 | ||||
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| Authors | ||||
Rania Gamal Abdelatif   1; Naglaa F Boraey2; Ghada Ashry Borham 3
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| 1Pediatric department, Faculty of Medicine, Sohag University, Egypt | ||||
| 2Pediatric department, Faculty of medicine, Sohag University, Egypt | ||||
| 3Pediatric department Sohag Faculty of medicine Sohag University | ||||
| Abstract | ||||
| Background: Unilateral multicystic dysplastic kidney is characterized by formation of multiple, non-communicating cysts with non- functioning renal parenchyma, and ureteral hypoplasia. It is a common kidney and urinary tract anomaly that can be detected via antenatal ultrasound examination. However, studies on this disease in Egypt are scarce. Objective of the study: was to study the characteristics and outcome of the children with unilateral multicystic dysplastic kidney. Patients and Methods: We retrospectively collected clinico-demographic, radiological and laboratory data of children with unilateral multicystic dysplastic kidney at pediatric nephrology clinic of Sohag University Hospital from January 2015 till February 2023. Results: A total of 35 patients [18(51.4%) boys 17(48.6%) girls] were followed for a median duration of 14.7 months with Interquartile range (3-31) months. Multicystic dysplastic kidney was located on the right and left sides in 23(65.7%) and 12 (34.3%) children, respectively. Most cases (74%) were detected via an antenatal ultrasound examination. About 43% of patients had at least one episode of urinary tract infection. Associated urogenital abnormalities were detected in 4 (11.4%) patients; one (2.9%) of them had vesicoureteral reflux with hydronephrosis in the contralateral side. One (2.9%) patient had persistent proteinuria and impaired kidney function. Overall 22 (62.9%) patients underwent partial or complete kidney involution. Conclusion: Most patients with unilateral multicystic dysplastic kidney are detected prenatally. The prognosis is generally good if the contralateral kidney is normal. Long-term follow up is essential to trace the development of proteinuria, hypertension or renal impairment. | ||||
| Keywords | ||||
| Multicystic dysplastic kidney; children; urogenital anomalies; vesicoureteral reflux; involution | ||||
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