Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.
Ali, A., Sallam, S., Ahmed, M., Attalla, E., Mohamed, A., Rshbek, M. (2024). Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.. EKB Journal Management System, 25(1), 13-23. doi: 10.21608/ejbbe.2024.233377.1065
Alzahraa Ali; Samira Mohammed Sallam; Mahmoud Meselhy Ahmed; Ehab Marouf Attalla; Abdelfattah Mohamed; Mona Rshbek. "Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.". EKB Journal Management System, 25, 1, 2024, 13-23. doi: 10.21608/ejbbe.2024.233377.1065
Ali, A., Sallam, S., Ahmed, M., Attalla, E., Mohamed, A., Rshbek, M. (2024). 'Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.', EKB Journal Management System, 25(1), pp. 13-23. doi: 10.21608/ejbbe.2024.233377.1065
Ali, A., Sallam, S., Ahmed, M., Attalla, E., Mohamed, A., Rshbek, M. Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.. EKB Journal Management System, 2024; 25(1): 13-23. doi: 10.21608/ejbbe.2024.233377.1065

Impact of Different Grid Sizes and Different Dose Calculation Algorithms on Dosimetric Parameters forHead and Neck IMRT.

Egyptian Journal of Biomedical Engineering and Biophysics
Volume 25, Issue 1, 2024, Pages 13-23    PDF (652.06 K)
Document Type: Original Article
DOI: 10.21608/ejbbe.2024.233377.1065
Authors
Alzahraa Ali* 1; Samira Mohammed Sallam2; Mahmoud Meselhy Ahmed3; Ehab Marouf Attalla4; Abdelfattah Mohamed1; Mona Rshbek1
1Physics Department, Faculty of Science, Benha University
2Physics department, faculty of science, Benha University.
3radiation oncology departement national cancer institute
4Radiotherapy & Nuclear Medicine Dep.; National Cancer Institute ; Cairo university
Abstract
Purpose: study the dosimetric impact of grid size and dose calculation algorithm on the intensity modulated radiotherapy (IMRT) plans for head and neck (H&N) cancer cases. Method: IMRT plans were generated in the MONACO® treatment planning system (TPS). That supports calculations to different algorithms (Monte Carlo (MC) and pencil beam (PB)) for patients already treated for H&N cancer. Retrieve patients and recalculate the plans by changing between grid size (2, 3, 4, 5 mm) and algorithm (MC and PB) for each plan. Dosimetric parameters for planning target volume (PTV) are minimum, maximum, and mean doses, D5%, V95%, homogeneity index (HI), conformity index (CI), and gradient index (GI). For organs at risk (OARs) maximum dose (Dmax), mean dose (Dmean). For the volume of the whole body (WB) receiving 2 Gy (V2Gy) and 5 Gy (V5Gy).
Results: 11 patients were enrolled in this study for analysis. Regarding HI and CI, MC plans show better results than PB plans. Comparing algorithms at the same grid size shows significance (P-value < 0.05) in all PTV parameters (except Dmin and mGI). Comparing grid sizes shows significance in only Dmax, Dmean, D5%, V95%, and CI2.
Keywords
Dosimetric evaluation; grid size; Monte Carlo; Pencil Beam; IMRT
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