Cardiovascular risk in psoriatic patients Relation to disease activity | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 25 February 2024 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2024.264817.1644 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Yara Assem   1; Fatma Ali Mohamed2; Hazem Mohammad Ali Farrag3; mostafa ahmed elsayed abuelela4; faten ismail5
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| 1Rheumatology and rehabilitation department | ||||
| 2Rheumatology and Rehabilitation department, faculty of medicine, minia university, El minia, Egypt | ||||
| 3Department of Cardiology, Faculty of Medicine, Minia University, Minia, Egypt | ||||
| 4clinical pathology , faculty of medicine , minia university | ||||
| 5rheumatology department minia university | ||||
| Abstract | ||||
| Background: Increased cardiovascular risk and subclinical atherosclerosis are linked to psoriatic illness. For the assessment of subclinical atherosclerosis (SA), carotid ultrasonography is helpful. Aim of the work: Determining the carotid intimal thickness (IMT) in individuals with psoriasis (PsO) who do not have cardiac disease. Patients and methods: Thirty healthy sex and age-matched controls and thirty PsO cases were included in this investigation. The carotid IMT was evaluated. SA was characterized by the presence of plaque and/or IMT >0.9 mm. The Psoriasis Area and Severity Index (PASI) was used to measure the disease activity in psoriasis. Body mass index, blood pressure, waist circumference, and lipid profile estimation were performed on all patients and controls. Results: PsO patients were 43.46 ± 13.94 years old on average, with 43.3% of them being female. IMT was 0.47±0.06 mm in control and in PsO (p<0.0001). In PsO, CIMT was substantially correlated with age (p<0.0001), disease duration (p=0.001), and PASI (p=0.001). Conclusions: In psoriatic disease, subclinical atherosclerosis has been connected to both disease activity and severity. | ||||
| Keywords | ||||
| Subclinical atherosclerosis; CIMT; Psoriasis | ||||
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