Effectiveness of COVID-19 vaccination among patients hospitalized from April 2020 to March 2021: A Retrospective cohort study | ||||
| Microbes and Infectious Diseases | ||||
| Article 2, Volume 5, Issue 2, May 2024, Page 408-419 PDF (579.42 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mid.2024.265857.1776 | ||||
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| Authors | ||||
Nehal Abdou Ali Khater  1; Inas Abd El Rahim Ali1; Rasha Saad Hussein2; Sahar Khalil Ibrahim2; Iman Mohamed Ahmed Bakr2
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| 1Department of Community and Family Medicine, Faculty of Medicine, Misr University for Science and Technology, Egypt | ||||
| 2Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Egypt | ||||
| Abstract | ||||
| Background: The COVID-19 pandemic is one of the worst pandemics of recent times. Getting vaccinated against COVID-19 is a preventative strategy that helps in the prevention of the infection and reduces its severity. This study aimed to measure the reinfection and vaccination rates among COVID-19 patients who were admitted to Ain Shams University (ASU) Hospitals during the pre-vaccination era (April 2020–March 2021) and correlate their vaccination status with the incidence and severity of the reinfection. Methods: A retrospective cohort study was conducted that includes patients diagnosed with SARS-CoV-2 infection and admitted to ASU Hospitals during the pre-vaccination era. Data about the first COVID-19 infection were extracted from the patient's records and then a random sample of patients was selected and data about vaccination and re-infection rates were collected from them through an interview questionnaire. Results: 340 out of the 400 included subjects received COVID-19 vaccination (85%); 4.41% received incomplete doses; 67.06% received full vaccination; and 28.23% received full vaccination with an additional booster dose. 53.61% of booster vaccinations used the same vaccine each time, while 46.39% received different vaccines. Regarding the reinfection rate, it was higher among the unvaccinated group compared to the vaccinated (20% versus 13.82%) but this difference was not statistically significant. Also, the length of stay in hospital during the reinfection was 6 days in both groups. Conclusion: Although our results revealed no statistically significant difference between the vaccinated and unvaccinated groups regarding the reinfection rate. But it may show a piece of evidence that COVID-19 vaccination plays an important clinical role in reducing the severity of COVID-19 infection. | ||||
| Keywords | ||||
| SARS-CoV-2 Efficiency; SARS-CoV-2 Vaccines; SARS-CoV-2 Re-infection; SARS-CoV-2 Immunization | ||||
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