QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS
Putra, G., Sumari, S., Sulistyowaty, M., Handajani, M., Suhud, F., Kesuma, D., Anwari, F. (2024). QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS. EKB Journal Management System, 47(1), 249-259. doi: 10.21608/bfsa.2024.261161.2000
Galih Satrio Putra; Sumari Sumari; Melanny Ika Sulistyowaty; Magdalena Sri Handajani; Farida Suhud; Dini Kesuma; Farida Anwari. "QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS". EKB Journal Management System, 47, 1, 2024, 249-259. doi: 10.21608/bfsa.2024.261161.2000
Putra, G., Sumari, S., Sulistyowaty, M., Handajani, M., Suhud, F., Kesuma, D., Anwari, F. (2024). 'QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS', EKB Journal Management System, 47(1), pp. 249-259. doi: 10.21608/bfsa.2024.261161.2000
Putra, G., Sumari, S., Sulistyowaty, M., Handajani, M., Suhud, F., Kesuma, D., Anwari, F. QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS. EKB Journal Management System, 2024; 47(1): 249-259. doi: 10.21608/bfsa.2024.261161.2000

QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS

Bulletin of Pharmaceutical Sciences Assiut University
Article 16, Volume 47, Issue 1, June 2024, Pages 249-259    PDF (1.78 M)
Document Type: Original Article
DOI: 10.21608/bfsa.2024.261161.2000
Authors
Galih Satrio Putra* 1; Sumari Sumari1; Melanny Ika Sulistyowaty2; Magdalena Sri Handajani3; Farida Suhud3; Dini Kesuma3; Farida Anwari4
1Department of Chemistry, Faculty of Mathematic and Natural Sciences, State University of Malang, Indonesia
2Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia
3Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia
4Medical Laboratory Science, University of Anwar Medika, Sidoarjo,Indonesia
Abstract
This research aims to analyze 500 samples for illicit drugs and NPS (New Psychoactive Substances) using GC-MS (Gas Chromatography Mass Spectrometry) in East Java Indonesia. Sample analysis was carried out by GC-MS with HP-5 column, injection port temperature of 250°C. Column temperature was maintained at 100°C for 2 minutes. It was then raised from10°C/minute to 280°C and maintained for 5 minutes Based on the results, it was detected 244 (48.8 %) Methamphetamine (MA); 30 (6 %) 3,4-Methylenedioxymethamphetamine (MDMA); 44 (8.8 %) 3,4-Methylenedioxyethylamphetamine (MDA); 56 (11.2 %) 3,4-Methylenedioxyethylamphetamine (MDEA); 106 (21.2 %) AB-Fubinaca; 5 (1.0 %) Tramadol; 5 (1.0 %) Ketamine; and 10 (2.0 %) Mephedrone. The identification of illicit drugs and NPS in confiscated materials was successfully achieved via GC-MS. The availability of GC-MS libraries is of great assistance in the identification of new drugs. Alternatively, the study of characteristic molecule fragments combined with the determination of their accurate masses can be a useful approach to identify unknown samples that were not previously analyzed.
Keywords
Qualitative Analysis; illicit drugs; NPS; GC-MS
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