QUALITATIVE ANALYSIS FOR ILLICIT DRUGS AND NPS (NEW PSYCHOACTIVE SUBSTANCES) USING GC-MS | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Articles in Press, Accepted Manuscript, Available Online from 10 March 2024 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2024.261161.2000 | ||||
View on SCiNiTO | ||||
Authors | ||||
Galih Satrio Putra 1; Sumari Sumari 1; Melanny Ika Sulistyowaty 2; Magdalena Sri Handajani3; Farida Suhud3; Dini Kesuma 3; Farida Anwari4 | ||||
1Department of Chemistry, Faculty of Mathematic and Natural Sciences, State University of Malang, Indonesia | ||||
2Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia | ||||
3Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia | ||||
4Medical Laboratory Science, University of Anwar Medika, Sidoarjo,Indonesia | ||||
Abstract | ||||
This research aims to analyze 500 samples for illicit drugs and NPS (New Psychoactive Substances) using GC-MS (Gas Chromatography Mass Spectrometry) in East Java Indonesia. Sample analysis was carried out by GC-MS with HP-5 column, injection port temperature of 250°C. Column temperature was maintained at 100°C for 2 minutes. It was then raised from10°C/minute to 280°C and maintained for 5 minutes Based on the results, it was detected 244 (48.8 %) Methamphetamine (MA); 30 (6 %) 3,4-Methylenedioxymethamphetamine (MDMA); 44 (8.8 %) 3,4-Methylenedioxyethylamphetamine (MDA); 56 (11.2 %) 3,4-Methylenedioxyethylamphetamine (MDEA); 106 (21.2 %) AB-Fubinaca; 5 (1.0 %) Tramadol; 5 (1.0 %) Ketamine; and 10 (2.0 %) Mephedrone. The identification of illicit drugs and NPS in confiscated materials was successfully achieved via GC-MS. The availability of GC-MS libraries is of great assistance in the identification of new drugs. Alternatively, the study of characteristic molecule fragments combined with the determination of their accurate masses can be a useful approach to identify unknown samples that were not previously analyzed. | ||||
Keywords | ||||
Qualitative Analysis; illicit drugs; NPS; GC-MS | ||||
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