Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts
Halim, H., Gad, M., Nada, H., Ali, M. (2024). Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts. EKB Journal Management System, 27(2), 0-0. doi: 10.21608/scumj.2024.345566
Halim M. Halim; Mohammed EM. Gad; Hesham A. Nada; Mohamed AM. Ali. "Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts". EKB Journal Management System, 27, 2, 2024, 0-0. doi: 10.21608/scumj.2024.345566
Halim, H., Gad, M., Nada, H., Ali, M. (2024). 'Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts', EKB Journal Management System, 27(2), pp. 0-0. doi: 10.21608/scumj.2024.345566
Halim, H., Gad, M., Nada, H., Ali, M. Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts. EKB Journal Management System, 2024; 27(2): 0-0. doi: 10.21608/scumj.2024.345566

Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts

Suez Canal University Medical Journal
Article 6, Volume 27, Issue 2, February 2024, Page 0-0  XML
Document Type: Original Article
DOI: 10.21608/scumj.2024.345566
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Authors
Halim M. Halim email orcid 1; Mohammed EM. Gad2; Hesham A. Nada1; Mohamed AM. Ali1
1Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Suez Canal University, Egypt.
2Dikirnis General Hospital, Mansoura, Egypt.
Abstract
Background:Anogenital warts treatment has always been a demanding entity.  Although several therapeutic options exist, no single modality is completely effective in its treatment rather than preventing recurrence. Aim: To assess the effectiveness ofmicroneedling-assisted topical bleomycin versus cryotherapy in the treatment of anogenital warts. Methods:This trial involved 36 patientswho were split into two groups. Group (A): bleomycin (n=18). Group (B): cryotherapy (n=18). In group (A), microneedling was performed on the lesion followed by spraying of bleomycin (1 U/mL) every two weeks for a total of four sessions. In group (B), Cryotherapy was employed at a two-week interval for a maximum of 4 sessions. Results:By the end of sessions, 15(83.3%) patients in the bleomycin group and 11(61.1%) patients in the cryotherapy group showed complete response of all the warts with a statistically significant difference (P = 0.039).Also, the percentage of improvement was significantly higher in warts with lower duration among both groups. After 6 months, Recurrence was reported only in two (13.3%) patients in the bleomycin group compared to five (45.5%) in the cryotherapy group with a statistically insignificant difference (p=0.095). Conclusion: In treating anogenital warts, microneedling-assisted topical bleomycin is more effective than cryotherapy.
 
Keywords
Anogenital warts; Bleomycin; Cryotherapy; Microneedling
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