Level of cardiac troponin T in relation to disease severity and outcomes in neonates with respiratory distress | ||||
| Benha Medical Journal | ||||
| Articles in Press, Accepted Manuscript, Available Online from 14 March 2024 PDF (242.5 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2024.234387.1891 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Effat Hussein Assar1; Shaheen Aly Yasin Dabour1; Yasser Mahmoud Ismail2; sarah adel sanad  3; Rasha Aguib Hassan4
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| 1Department of Pediatrics, Faculty of Medicine- Benha University | ||||
| 2Department of clinical pathology, Faculty of medicine- Benha University | ||||
| 3pediatric department benha university | ||||
| 4Department of Pediatrics Faculty of Medicine - Benha University | ||||
| Abstract | ||||
| Background: The purpose of this study was to assess cardiac troponin T(cTnT) in neonates with respiratory distress as a marker of myocardial dysfunction.. Methods: : Total sample size 100 neonate , 50 neonates with RD and 50 healthy neonate (without RD) .. Serum cardiac troponin T was measured using ELISA technique. Results: the cardiac troponin T (CTnT) levels among our studied groups, We found CTnT levels were significantly higher (p < 0.001) in study group (RD cases )( 0.200±0.156 ng/ml) than in control group (healthy neonates ) (0.034±0.019 ng/ml) .Area under the ROC curve was 0.962 with best cutoff value(>0.056), sensitivity was 90%, specificity was 90%. Also, cTnT levels were significantly higher in neonates who required inotropic support when compared to those without inotropes. We found CTnT levels were significantly higher in cases who died than in cases who survived (p < 0.001). Conclusion: Cardiac troponin T is higher in neonates with respiratory distress compared to healthy infants. It could be used as a useful marker for myocardial dysfunction. | ||||
| Keywords | ||||
| Cardiac troponin T; respiratory distress; neonates | ||||
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