Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt | ||||
| Parasitologists United Journal | ||||
| Articles in Press, Accepted Manuscript, Available Online from 15 March 2024 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/puj.2024.263033.1235 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Marwa A. Gouda   1; Ahmed S. Abdelgawad2; Hind S. AboShabaan3; Marwa Sabry Rizk4; Asmaa F Ibrahim 5
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| 1Menoufia | ||||
| 2clinical pathology department, National Liver Institute, Menoufia University | ||||
| 3Clinical Pathology Department, National Liver Institute, Menoufia University, Shebin El-Kom, Menoufia, ,Egypt | ||||
| 4Department of hepatology, gastroenterology and nutrition, National Liver Institute, Menoufia University, Menoufia, Egypt | ||||
| 51Department of Clinical and Molecular Parasitology, National Liver Institute, Menoufia University, Menoufia, Egypt | ||||
| Abstract | ||||
| Background: Determination of the prevalence of human toxocariasis is a priority considering the sustained developmental goals of WHO by 2030 and the recent climatic changes. Objective: To detect the seroprevalence of toxocariasis among eosinophilic children in Shibin El Kom, Menoufia Governorate, Egypt. Subjects and Methods: The study included 300 randomly selected eosinophilic children for whom stool analysis was performed. Ninety-six of the children positive for other parasitic infections were excluded from the study to avoid cross-reactivity. The remaining 204 children with negative stool analysis were subjected to the detection of Toxocara antibodies using ELISA. Results: Seropositivity of Toxocara antibodies among examined children was 15.7% (32/204), and 84.3% (172/204) were negative. Their ages ranged from 5 to 17 years, with a mean age of 9.16±3.11 years. Suspicious clinical history was recorded in 94.1% (192/204) of children; 15.7% (32/204) had a history of recurrent fever of unknown origin, 21.6% (44/204) children were asthmatic, and cutaneous manifestations were observed in 2% (4/204) of cases. None of the patients had ocular or hepatic disorders. The history of direct contact with pets was present in 15.7% (32/204) of patients with non-significant differences to negative children. Conclusion: Our study reported a relatively higher prevalence of seropositivity to toxocariasis among children with eosinophilia in Shibin El Kom City, Menoufia Governorate, Egypt. Therefore, implementing studies on a larger scale would provide more knowledge on the spread of this parasite in Egypt, and enhance advanced approaches to improve its control. | ||||
| Keywords | ||||
| Children; Egypt; ELISA; eosinophilia; toxocariasis; neglected diseases | ||||
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