Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages
Ezzat Eldesouki, M., Warda, O., Abdelhafez, H., Abdelrazek, M. (2024). Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages. EKB Journal Management System, 28(1), 39-50. doi: 10.21608/egyfs.2024.345928
Mohamed Abdelmawla Ezzat Eldesouki; Osama Mahmoud Warda; Hanan Nabil Abdelhafez; Mahmoud Mohamed Abdelrazek. "Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages". EKB Journal Management System, 28, 1, 2024, 39-50. doi: 10.21608/egyfs.2024.345928
Ezzat Eldesouki, M., Warda, O., Abdelhafez, H., Abdelrazek, M. (2024). 'Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages', EKB Journal Management System, 28(1), pp. 39-50. doi: 10.21608/egyfs.2024.345928
Ezzat Eldesouki, M., Warda, O., Abdelhafez, H., Abdelrazek, M. Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages. EKB Journal Management System, 2024; 28(1): 39-50. doi: 10.21608/egyfs.2024.345928

Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages

The Egyptian Journal of Fertility of Sterility
Article 6, Volume 28, Issue 1 - Serial Number 11106352, January 2024, Page 39-50  XML PDF (3.97 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2024.345928
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Authors
Mohamed Abdelmawla Ezzat Eldesouki email 1; Osama Mahmoud Warda1; Hanan Nabil Abdelhafez2; Mahmoud Mohamed Abdelrazek2
1Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt
2Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt
Abstract
Background: Molar pregnancy is a rare complication of pregnancy characterized by the abnormal growth of trophoblasts, the cells that normally develop into the placenta. Routine histopathologic examination of uterine products is beneficial in protecting obstetrician and gynecologist from medico legal recrimination, but it is unclear whether this practice is medically justified.  
Objective: The aim of this study is to evaluate Prevalence of molar pregnancy in histopathological examination of products of conception following first trimester miscarriages.
Patients and Methods: This was a cross sectional study conducted on cases with products of conception in the first trimester miscarriages up to 12 weeks gestation. Entire cases were subjected to full history taking, clinical examination after that the samples were collected via manual vacuum aspiration for histopathological analysis.
Results: The prevalence of molar pregnancy among the studied cases was 7%. About 93% of the studied cases were normal. Most of the studied histological specimens were products of conception which accounts for 85% of cases. The incidence of complete vesicular mole, degenerated Products of conception, Hyper secretory Endometrium, Infected Products of conception, Necrotic Products of conception and Partial Hydatidiform moles were 4.2, 1.4, 2.8, 1.4, 1.4 and 2.8 respectively.
Conclusion: Histopathological examination seemed to be a promising tool in the context of assessment of products of conception in which the prevalence of molar pregnancy was 7%. In addition, incidence of molar pregnancy has no significant correlations with all clinical features as well as with blood groups.
Keywords
Keywords: Molar pregnancy; Histopathological examination; Products of conception. 
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