Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy
Taema, M., Sweed, A., Radwan, A. (2024). Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy. EKB Journal Management System, 28(1), 51-56. doi: 10.21608/egyfs.2024.345929
Mohamed I. Taema; Amr Sobhy Sweed; Ahmed M. Radwan. "Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy". EKB Journal Management System, 28, 1, 2024, 51-56. doi: 10.21608/egyfs.2024.345929
Taema, M., Sweed, A., Radwan, A. (2024). 'Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy', EKB Journal Management System, 28(1), pp. 51-56. doi: 10.21608/egyfs.2024.345929
Taema, M., Sweed, A., Radwan, A. Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy. EKB Journal Management System, 2024; 28(1): 51-56. doi: 10.21608/egyfs.2024.345929

Urine albumin/creatinine ratio for the assessment of albuminuria in hypertensive disorders of pregnancy

The Egyptian Journal of Fertility of Sterility
Article 7, Volume 28, Issue 1 - Serial Number 11106352, January 2024, Page 51-56  XML PDF (2.25 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2024.345929
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Authors
Mohamed I. Taema email 1; Amr Sobhy Sweed1; Ahmed M. Radwan2
1Obstetrics and gynecology department, faculty of medicine, Ain shams University
2Obstetrics & Gynecology Department, Faculty of Medicine, Zagazig University
Abstract
Background: The Protein-Creatinine ratio (P/C Ratio) measurement is an alternative diagnostic method for quantitatively evaluating proteinuria in pre-eclampsia. This study aimed to assess the precision of the protein/creatinine ratio as a diagnostic tool for proteinuria in preeclamptic pregnant patients.  
Methods: A prospective study was conducted at the Obstetrics and Gynecology Department of a private hospital in KSA from July 2021 to January 2023, 100 pregnant women with preeclampsia were included in the study. All patients in the study underwent a history taking, physical examination, routine laboratory investigations, and urine protein/creatinine ratio assessment.  
Results: The findings found substantial positive connections between 24-hour protein, proteinuria, and serum creatinine, as well as strong positive P/C ratio and 24-hour protein correlations. Urine creatinine and P/C ratio were shown to have strong negative correlations. The P/C ratio needs to be less than 0.29 to detect more than 300 mg of protein excretion per 24 hours, detecting 300 mg/24 hours of protein excretion with sensitivity of 95.3% and specificity of 71%.
Conclusion: Random PCR may be employed in urgent situations as a quick, simple, and accurate diagnostic for the detection of substantial proteinuria in hypertensive diseases during pregnancy.
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