The Significance of High-Sensitivity Cardiac Troponin T with Left Ventricular Strain in Heart Failure with Preserved Ejection Fraction

El-shetry, Mohamed Saad; Mahfouz, Ragab Abdelsalam; Amin, Mohamed Ibrahim; Arab, Mohamed; Alteb, Mohammed Abdallah OMAR; Taha, Mohamed Mesbah

doi:10.21608/zumj.2024.274251.3227

	The Significance of High-Sensitivity Cardiac Troponin T with Left Ventricular Strain in Heart Failure with Preserved Ejection Fraction
Zagazig University Medical Journal
Article 18, Volume 30, Issue 9.1, December 2024, Page 4941-4951 PDF (456.65 K)
Document Type: Original Article
DOI: 10.21608/zumj.2024.274251.3227
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Authors
Mohamed Saad El-shetry ¹; Ragab Abdelsalam Mahfouz²; Mohamed Ibrahim Amin³; Mohamed Arab²; Mohammed Abdallah OMAR Alteb ⁴; Mohamed Mesbah Taha²
¹Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
²Cardiology Department, Faculty of Medicine, Zagazig University
³Zagazig university. Faculty of medicine, cardiology department
⁴M.B.B.Ch, Tripoli University, Libya
Abstract
Background: There is not enough information available at this time to determine if patients with stable heart failure and preserved ejection fraction also experience higher left ventricular strain and high-sensitivity troponin, which are associated with a worsening of the condition. Aim: To predict and early diagnose left ventricular dysfunction in patients with heart failure with preserved ejection fraction Methods: This case control study was conducted on 48 subjects diagnosed with HFpEF, at Cardiology Department, Faculty of Medicine, Zagazig University. The patients were divided into 2 equal groups: case group (n=24): included patients diagnosed with HFpEF with diastolic dysfunction and control group (n=24): included healthy individuals. High-sensitivity cardiac troponin T and left ventricular strain were assessed in all subjects. Results: High sensitivity cardiac troponin T, GLS, GDSIVR, GDSE, SRE, E/SRE and SRIVR were considerably greater in the cases group as opposed to the control group (P<0.05). Conclusion: In comparison to normal controls, our investigation revealed that HFpEF patients with diastolic dysfunction had significantly higher hs-cTnT levels, more severe anomalies in left ventricular strain, and more advanced diastolic dysfunction.
Keywords
High-Sensitivity Cardiac Troponin T; Left Ventricular Strain; HFpEF


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